Results 51 to 60 of about 115,986 (227)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Multi–Output Classification Based on Convolutional Neural Network Model for Untrained Compound Fault Diagnosis of Rotor Systems with Non–Contact Sensors

open access: yesSensors, 2023
Fault diagnosis is important in rotor systems because severe damage can occur during the operation of systems under harsh conditions. The advancements in machine learning and deep learning have led to enhanced performance of classification. Two important
Taehwan Son, Dongwoo Hong, Byeongil Kim
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

MintHint: Automated Synthesis of Repair Hints

open access: yes, 2013
Being able to automatically repair programs is an extremely challenging task. In this paper, we present MintHint, a novel technique for program repair that is a departure from most of today's approaches. Instead of trying to fully automate program repair,
Cadar C.   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Geochemistry and origin of organic-rich sediment veins in fractured granitic basement, Helmsdale, Sutherlandshire, UK [PDF]

open access: yes, 2017
Acknowledgements MB is in receipt of a PhD studentship from the Petroleum Technology Development Fund of Nigeria. LB is supported by NERC grant NE/M010953/1. C. Taylor, W. Ritchie and J. Johnston provided skilled technical support.
Baba, Mas'Ud   +3 more
core   +1 more source

Fault Separation and Detection for Compound Bearing-Gear fault Condition Based on Decomposition of Marginal Hilbert Spectrum [PDF]

open access: yesIEEE Access, 2019
For the rotating machinery system, it is a challenge to explore fault detection and diagnosis for multiple-faults condition, which simultaneously contains faulty bearing components and faulty gear components. In the study, a fault feature separation and extraction approach is proposed for the bearing-gear fault condition through combining empirical ...
Changning Li   +5 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Compound Fault Diagnosis of Planetary Gearbox Based on Improved LTSS-BoW Model and Capsule Network

open access: yesSensors
The identification of compound fault components of a planetary gearbox is especially important for keeping the mechanical equipment working safely. However, the recognition performance of existing deep learning-based methods is limited by insufficient ...
Guoyan Li   +5 more
doaj   +1 more source

Dynamic Modeling and Analysis of Rolling Bearing with Compound Fault on Raceway and Rolling Element

open access: yesShock and Vibration, 2020
Rolling element bearing is a very important part of mechanical equipment and widely used in rotating machinery. Rolling element bearings could appear localized defects during the working condition, which would cause the complex vibration response of ...
Xin Zhang   +5 more
doaj   +1 more source

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