Results 81 to 90 of about 122,093 (281)

A Compound fault diagnosis for rolling bearings method based on blind source separation and ensemble empirical mode decomposition.

PLoS ONE, 2014
A Compound fault signal usually contains multiple characteristic signals and strong confusion noise, which makes it difficult to separate week fault signals from them through conventional ways, such as FFT-based envelope detection, wavelet transform or ...
Huaqing Wang, Ruitong Li, Gang Tang, Hongfang Yuan, Qingliang Zhao, Xi Cao   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Toward compound fault diagnosis via EMAGAN and large kernel augmented few-shot learning

Frontiers in Mechanical Engineering
Bearings are essential in machinery. Damage to them can cause financial losses and safety risks at industrial sites. Therefore, it is necessary to design an accurate diagnostic model.
Wenchang Xu, Zhexian Zhang, Zhijun Wang, Tianao Wang, Zijian He, Shijie Dong   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Dynamic Characteristics of Gear System Under Compound Fault of Tooth Root Crack and Bearing Outer Ring

Machines
Research on single faults like tooth root cracks and bearing outer ring failures is well-established. However, existing studies often replace the actual crack propagation path with a simplified linear crack model, neglecting the variation in stress ...
Yu Bai, Hong Jiang, Xiangfeng Zhang, Zhen Lei, Wenhan Huang, Zhijie Zhu, Chaochao Cui   +6 more
doaj   +1 more source

Isolation and Identification of Compound Faults in Rotating Machinery via Adaptive Deep Filtering Technique

IEEE Access, 2019
Compound defects commonly occur on rotating machinery under fatigue and heavy loads, and their fault signatures are coupled and easily buried in strong unwanted vibrations and background noise.
Chunlin Zhang, Yuling Liu, Fangyi Wan, Binqiang Chen, Jie Liu   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An architecture for object-oriented intelligent control of power systems in space [PDF]

A control system for autonomous distribution and control of electrical power during space missions is being developed. This system should free the astronauts from localizing faults and reconfiguring loads if problems with the power distribution and ...
Holmquist, Sven G., Jansen, Ben H., Jayaram, Prakash   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source