Results 201 to 210 of about 13,654 (302)

Topology‐Enriched Toughness Enhancement in Quasi‐Periodic Metastructures Featuring Tailorable Strong‐Weak Network

Advanced Science, EarlyView.
A quasi‐periodic Dart‐Kite (QDK) metastructure with a golden‐ratio‐constrained strong–weak bond network simultaneously enhances strength, toughness, and damage tolerance. Its distributed topology enables predictable, tailorable crack paths for precise fracture control and stable mechanics, demonstrating a high‐performance, controllable architecture ...
Tianyu Gao, Genda Wang, Jiabao Bai, Kai Liu   +3 more
wiley   +1 more source

N-benzylbenzamide derivative (SBM685) as a novel MDR1 inhibitor for overcoming 5 fluorouracil resistance in gastric cancer through computational and in vitro analysis. [PDF]

Discov Oncol
Al Fayi M, Dera AA.
europepmc   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Machine Learning (ML) and Molecular Dynamics-Driven Optimization of VEGFR2 Ligands against Hepatocellular Carcinoma. [PDF]

Oncol Res
Yasmeen F, Manan A, Kim W, Choi S.
europepmc   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Does Evenness Even Exist? [PDF]

Ecol Lett
Alroy J.
europepmc   +1 more source

A Worm‐Inspired Origami Robot with Multimodal Locomotion for Adaptive Mobility in Complex Pipeline Environments

Advanced Science, EarlyView.
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang, Kangning Tan, Zihan He, Hongsen Pang, Yanjie Wang, Hongbin Fang, Jian Xu   +6 more
wiley   +1 more source

Multicentre cohort study on the course of paediatric familial Mediterranean fever in the aftermath of the 2023 earthquake. [PDF]

BMJ Paediatr Open
Cam V, Yalcin SS, Batu ED, Kacmaz HM, Kocamaz NG, Günal Ö, Kayhan E, Bozkaya B, Taşkın S, Gungorer V, Kılıç Konte E, Pirim G, Ünal D, Ozdel S, Koker O, Pac Kısaarslan A, Kisla Ekinci RM, Dogantan Ş, Demir S, Ozturk K, Adıgüzel Dundar H, Basaran O, Balat A, Sozeri B, Kasapcopur O, Bilginer Y, Ozen S.   +26 more
europepmc   +1 more source

Suppressed Auger Heating of Hot Carriers in Cu‐Doped Colloidal Quantum Wells

Advanced Science, EarlyView.
ABSTRACT Auger heating represents a major bottleneck for hot carrier (HC) relaxation in colloidal quantum wells (CQWs), delaying carrier accumulation in band‐edge states and diminishing performance in light‐emitting applications. To address this issue, we introduce copper doping in CdSe CQWs to create midgap states, which efficiently suppresses Auger ...
Junhong Yu, Ke Wang, Yadong Han, Zhenzhong Lian, Songyan Hou, Hilmi Volkan Demir, Manoj Sharma   +6 more
wiley   +1 more source

On a multi-threshold compound Poisson process perturbed by diffusion

We consider a multi-layer compound Poisson surplus process perturbed by diffusion and examine the behaviour of the Gerber-Shiu discounted penalty function. We derive the general solution to a certain second order integro-differential equation.
Tsai, Cary Chi-Liang, Mitric, Ilie-Radu, Sendova, Kristina P.   +2 more
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