Results 101 to 110 of about 3,864,570 (332)
Veterinary Compounding: Regulation, Challenges, and Resources
Pharmaceutics, 2017 The spectrum of therapeutic need in veterinary medicine is large, and the availability of approved drug products for all veterinary species and indications is relatively small.
G. Davidson
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
THE STUDY OF WORD PLAY IN CAPEK COLOUMN [PDF]
, 2011 Language is a medium of communication which can be functioned to various aims, such as giving socialcriticism and factual issues, and showing attitude and perception of certain people to certain situation.The communication is sometimes spoken indirectly,
Oktiva Herry , Chandra
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Word formation in contemporary Liangmai: A morphological study [PDF]
, 2019 This paper attempts to discuss the different processes of word formation in contemporary Liangmai, a Tibeto-Burman (TB) language of the Kuki-Chin-Naga sub group (Bradley 1997).
Daimai, Kailadbou
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The significance of word formation techniques utilised in Northern Sotho plant names
LiteratorWord formation is a system of rules that can produce new words based on existing lexical items. Word formation strategies are employed by languages to develop their terminology or vocabulary. Although earlier studies have been conducted on Northern Sotho
Seleka M. Tembane
doaj +1 more source
COMPOUNDING OF BASEMAH LANGUAGE: An Effort to Understand the Uniqueness of Local Languages [PDF]
, 2017 The objectives of this research are to describe the compound and identify its kinds in Basemah language. Compound is words formed by combining roots, and the much smaller category of phrasal words, that is items that have internal structure of phrases ...
Mahdi, Sutiono
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source