Results 241 to 250 of about 955,174 (332)

Identification of Potential Anticancer Bioactive Compounds from Fractions of Alpinia monopleura Rhizome Extract

Wahyuni Wahyuni, Adryan Fristiohady, Idin Sahidin, Agung Wibawa Mahatva Yodha, La Ode Muhammad Julian Purnama, Loly Subhiaty Idrus, Muhammad Ilyas Y, Syafika Alaydrus, Wa Ode Sitti Musnina, Saipul Maulana   +9 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Assessment of Meropenem Stability in Meropenem Admixtures Using 2 g Vials and Normal Saline Prepared Using addEASE^® Connectors. [PDF]

Hosp Pharm
Gill CM, Sierra T, Kovarik N, Mays M, Lavoie T, Achour B.   +5 more
europepmc   +1 more source

Column‐Compound Extremes in the Global Ocean [PDF]

Joel Wong, Matthias Münnich, Nicolas Gruber   +2 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Development and application of a wipe sampling method for detection of antibiotic surface contamination in hospital wards. [PDF]

Ann Work Expo Health
Nilsson CA, Huynh E, Rashdan D, Tinnert A, Hedmer M, Kåredal M.   +5 more
europepmc   +1 more source

Irony Compounded [PDF]

Science, 1961
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Plants-occurring Anthraquinones as Photosensitive Compounds for Photodynamic Method: A Critical Overview [PDF]

Vanya Mantareva, Diana Braikova, Irına Lazarova, Tsanislava Genova   +3 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source