Results 101 to 110 of about 101,543 (348)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Economic Evaluation of Ready-to-Dilute Thiotepa (Tepylute®): Institutional Cost Offsets and Time Savings Compared to Lyophilized Thiotepa in a United States Hospital Pharmacy

ClinicoEconomics and Outcomes Research
Orlaith Ryan,1 Maurice Clancy,1 Alanna MacDonald,2 Laura Pastor,2 Megan Bourque2 1Shorla Oncology, Clonmel, Co., Tipperary, Ireland; 2Value and Evidence Department, EVERSANA, Burlington, ON, CanadaCorrespondence: Orlaith Ryan, Shorla Oncology, Questum ...
Ryan O, Clancy M, MacDonald A, Pastor L, Bourque M   +4 more
doaj  

Outcomes of major cardiac operations are not improved for black patients at black-serving institutionsCentral MessagePerspective

JTCVS Open
Objective: Although provider–patient racial concordance has been associated with improved outcomes among patients of Black race, it is unclear if increased representation at the institutional level is associated with the same benefits.
Nikhil L. Chervu, MD, MS, Saad Mallick, MD, Amulya Vadlakonda, BS, Sara Sakowitz, MS, MPH, Ifigenia Oxyzolou, Troy Coaston, BS, Peyman Benharash, MD   +6 more
doaj   +1 more source

Agricultural Credit Under Economic Liberalization And Islamization In Sudan [PDF]

This study uses survey data to examine the operations of the agrarian credit market,formal and informal, in Sudan under conditions of recent economic liberalization and Islamization; the latter does not allow interest rate fixing.
Adam B. Elhiraika, Sayed A. Ahmed
core  

Utilization and Costs of Compounded Medications for Commercially Insured Patients, 2012-2013 [PDF]

, 2016
Timothy McPherson, Patrick E. Fontane, Reethi Iyengar, Rochelle Henderson   +3 more
openalex   +1 more source

Overcoming Compound Racial Inequity: Policies and Costs for Closing the Black-White Wealth Gap [PDF]

, 2022
Jonathan Welburn, Pedro Nascimento de Lima, Krishna B. Kumar, Osonde Osoba, Jonathan Lamb   +4 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Youth Incarceration, Health, and Length of Stay [PDF]

, 2017
For youth from marginalized communities, the pathway into the juvenile justice system occurs against a backdrop of disproportionately high levels of stress, complex trauma, and adverse childhood experiences.
González, Thalia
core   +1 more source

Optimal dividend-penalty policies for a piecewise-deterministic compound Poisson risk model with transaction costs

, 2023
Qingyun Zheng, Yuying Liu
openalex   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source