Results 71 to 80 of about 101,543 (348)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Energy efficiency interventions in UK higher education institutions

open access: yes, 2010
This paper provides an insight into energy efficiency interventions studies, focusing on issues arising in UK higher education institutions (HEIs) in particular Based on a review of the context for energy efficiency and carbon reduction programmes in the
Altan, H.
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

TASA: A New Task Scheduling Algorithm in Cloud Computing [PDF]

open access: yesJournal of Advances in Computer Engineering and Technology, 2015
Cloud computing refers to services that run in a distributed network and are accessible through common internet protocols. It merges a lot of physical resources and offers them to users as services according to service level agreement.
Somayeh Taherian Dehkordi   +1 more
doaj  

Direct cost of dengue hospitalization in Zhongshan, China: Associations with demographics, virus types and hospital accreditation.

open access: yesPLoS Neglected Tropical Diseases, 2017
BackgroundZhongshan City of Guangdong Province (China) is a key provincial and national level area for dengue fever prevention and control. The aim of this study is to analyze how the direct hospitalization costs and the length of stay of dengue ...
Jing Hua Zhang, Juan Yuan, Tao Wang
doaj   +1 more source

Neologisms in Modern English: study of word-formation processes [PDF]

open access: yes, 2013
http://tartu.ester.ee/record=b2654513~S1 ...
Gontšarova, Julia
core  

Consumer Litigation Funding: Just Another Form of Payday Lending? [PDF]

open access: yes, 2014
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces permanent neurochemical and functional deficits. Following the administration of either two or four injections of the dopamine neurotoxin, MPTP, at a dose of 40 mg/kg, C57/BL6 mice were given ...
Archer, Trevor   +2 more
core   +3 more sources

Compound Poisson Disorder Problems with Nonlinear Detection Delay Penalty Cost Functions [PDF]

open access: yesSequential Analysis, 2010
Abstract The quickest detection of the unknown and unobservable disorder time, when the arrival rate and mark distribution of a compound Poisson process suddenly changes, is formulated in a Bayesian setting, where the detection delay penalty is a general smooth function of the detection delay time.
openaire   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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