Results 221 to 230 of about 4,026 (283)

A framework for conducting clinical trials involving 3D printing of medicines at the point-of-care. [PDF]

open access: yesDrug Deliv Transl Res
Parramon-Teixido CJ   +7 more
europepmc   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Drug shortages: clinical implications and burdens - a trinational multiple-methods study including key stakeholders. [PDF]

open access: yesJ Pharm Policy Pract
Rose O   +7 more
europepmc   +1 more source

Modulating Surface‐Active Hydrogen for Facilitating Nitrate‐to‐Ammonia Electroreduction on Layered Double Hydroxides Nanosheets

open access: yesAdvanced Functional Materials, EarlyView.
The NiCuFe‐layered double hydroxides nanosheets are synthesized for facilitating nitrate‐to‐ammonia with a high ammonia yield of 1.64 mmol h−1 cm−2, Faradaic efficiency of 94.8% and stability for 15 cycles. The assembled Zn‐nitrate battery delivers a remarkable power density of 12.4 mW cm−2.
Bin Liu   +9 more
wiley   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy