Results 121 to 130 of about 1,404,239 (332)

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, Volume 599, Issue 9, Page 1317-1336, May 2025.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

Experimental Approaches to Referential Domains and the On-Line Processing of Referring Expressions in Unscripted Conversation

open access: yesInformation, 2011
This article describes research investigating the on-line processing of language in unscripted conversational settings. In particular, we focus on the process of formulating and interpreting definite referring expressions.
Sarah Brown-Schmidt   +1 more
doaj   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, Volume 599, Issue 8, Page 1094-1112, April 2025.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

Grasping the Interplay between the Verbal Cultural Diversity and Critical Thinking, and Their Consequences for African American Education

open access: yesFrontiers in Education, 2017
The role language has in human learning has been discussed in the context of its impact on culture through African American communities. A strong link between thinking and language through the framework of question asking was reported.
Horace Crogman, Horace Crogman
doaj   +1 more source

A comparison of the comprehension of procedural information using computer and hard-copy media

open access: yes, 1993
Users of technical procedures must be able to understand the documents to use them to perform their work. As more companies contemplate putting their procedures on-line, it is important to know whether computer systems will be as effective as traditional
Lawrence, Aiessa Moyna
core  

The Role of Involvement in Attention and Comprehension Processes

open access: yes, 1988
We present the results of a study designed to test several hypotheses concerning the effects of intrinsic and situational sources of personal relevance on felt involvement and on the amount of attention and comprehension effort, the focus of attention ...
Richard L. Celsi, J. Olson
semanticscholar   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

open access: yesFEBS Letters, Volume 599, Issue 7, Page 971-988, April 2025.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin   +2 more
wiley   +1 more source

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