Results 171 to 180 of about 59,555 (253)

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

Optimizing type 2 diabetes management in older adults with cancer through comprehensive geriatric assessment-guided medication reviews: a monocentric retrospective study. [PDF]

BMC Geriatr
Guerra C, Correard F, Montégut C, Nakache J, Arcani R, Di Mascio T, Villani P, Honoré S, Daumas A, Couderc AL, Bérard C.   +10 more
europepmc   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

Comprehensive Geriatric Assessment in primary healthcare: a scoping review protocol. [PDF]

BMJ Open
Vidinha Pereira AL, Vaz A, Paúl C, Santiago L, Rosendo I.   +4 more
europepmc   +1 more source

MELD score predicts outcomes in patients with advanced heart failure: A longitudinal evaluation

ESC Heart Failure, Volume 12, Issue 2, Page 839-847, April 2025.
Abstract Aims Advanced heart failure (AHF) is characterized by recurrent episodes of haemodynamic instability and frequent hospitalizations, leading to a progressive decline in quality of life and high mortality rates. The objectives of this study were to evaluate the effect of the model for end‐stage liver disease (MELD) score and its variations in ...
Francesco Curcio, Cristiano Amarelli, Rosaria Chiappetti, Irene Mattucci, Veronica Flocco, Mahmoud Issa Rammal, Ciro Abete, Francesca Mazzella, Ciro Maiello, Pasquale Abete, Francesco Cacciatore   +10 more
wiley   +1 more source

Evaluating the Cost-Effectiveness of Comprehensive Geriatric Assessment: Protocol for a Systematic Review of Economic Evaluations. [PDF]

HRB Open Res
Yigezu A, Galvin R, Trépel D.
europepmc   +1 more source

Real‐world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study

ESC Heart Failure, Volume 12, Issue 2, Page 1203-1216, April 2025.
The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies, Svenja Ney, Ingrid Kindermann, Yvonne Bewarder, Angela Zimmer, Fabian Knebel, Katrin Hahn, Sebastian Spethmann, Peter Luedike, Lars Michel, Tienush Rassaf, Maria Papathanasiou, Stefan Störk, Vladimir Cejka, Amin Polzin, Fabian Voss, Malte Kelm, Bernhard Unsöld, Christine Meindl, Michael Paulus, Ali Yilmaz, Bishwas Chamling, Caroline Morbach, Roman Pfister   +23 more
wiley   +1 more source

The relationship between vitamin D levels, comprehensive geriatric assessment and anthropometric measurements. [PDF]

PLoS One
Cakir M, Ozkaya Y, Terzi NE, Aygun O, Kucukerdem HS, Saki E.   +5 more
europepmc   +1 more source

Management of Radiodermatitis in Patients With Head and Neck Cancer Undergoing Radiotherapy: A Scoping Review

Health Care Science, EarlyView.
The data obtained through this review highlight the lack of global consensus among radiotherapy centers on the best topical treatment for radiodermatitis. It indicates that the choice of treatment depends on professional judgment due to the absence of standardized guidelines, pointing to the need for more robust scientific research to develop effective
Tâmara Taynah Medeiros da Silva, Louise Constancia de Melo Alves Silva, Thatiane Evelyn de Lima Fernandes, Karena Cristina da Silva Leal, Thaís Brunna Maurício Pinheiro, Guilherme Moises Alves Fernandes, Kátia Regina Barros Ribeiro, Daniele Vieira Dantas, Rodrigo Assis Neves Dantas   +8 more
wiley   +1 more source

An efficient non-invasive model for predicting cognitive impairment based on comprehensive geriatric assessment: Machine learning and SHAP analysis. [PDF]

J Alzheimers Dis Rep
Zhang J, Li W, Wen S, Zhang X, Gao Y, Feng Y, Lü Y.   +6 more
europepmc   +1 more source