Results 51 to 60 of about 4,167,463 (302)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Efficient Compression Technique for Sparse Sets [PDF]

, 2018
Recent technological advancements have led to the generation of huge amounts of data over the web, such as text, image, audio and video. Most of this data is high dimensional and sparse, for e.g., the bag-of-words representation used for representing text.
Rameshwar Pratap, Ishan Sohony, Raghav Kulkarni   +2 more
openaire   +3 more sources

Compressed Vision for Efficient Video Understanding

, 2023
Experience and reasoning occur across multiple temporal scales: milliseconds, seconds, hours or days. The vast majority of computer vision research, however, still focuses on individual images or short videos lasting only a few seconds. This is because handling longer videos require more scalable approaches even to process them.
Olivia Wiles, João Carreira 0001, Iain Barr, Andrew Zisserman, Mateusz Malinowski   +4 more
openaire   +3 more sources

Dictionary sharing: An efficient cache compression scheme for compressed caches [PDF]

2016 49th Annual IEEE/ACM International Symposium on Microarchitecture (MICRO), 2016
The effectiveness of a compressed cache depends on three features: i) the compression scheme, ii) the compaction scheme, and iii) the cache layout of the compressed cache. Skewed compressed cache (SCC) and yet another compressed cache (YACC) are two recently proposed compressed cache layouts that feature minimal storage and latency overheads, while ...
Panda, Biswabandan, Seznec, André
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Efficient URL and URI Compression

2024 33rd International Conference on Computer Communications and Networks (ICCCN)
Web applications use Universal Resource Identifiers (URIs), interchangeably referred to as Uniform Resource Locators (URLs), to locate resources such as files and web pages on the Internet. Messaging services, firewalls, content distribution frameworks, event logs, databases and datasets store countless URIs.
Felix Savins, Kevin Saric, Gowri Sankar Ramachandran, Raja Jurdak   +3 more
openaire   +2 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

ACTF: An efficient lossless compression algorithm for time series floating point data

Journal of King Saud University: Computer and Information Sciences
The volume of time series data across various fields is steadily increasing. However, this unprocessed massive data challenges transmission efficiency, computational arithmetic, and storage capacity.
Weijie Wang, Wenhui Chen, Qinhon Lei, Zhe Li, Huihuang Zhao   +4 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source