Results 51 to 60 of about 30,637 (266)
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
The physical dimensions of the compressed breast
The success of the National Breast Screening Program relies on accurate dose measurements, essential for any risk–benefit analysis and radiation protection considerations (Forrest, 1986). This need to measure absorbed doses within and around the irradiated breast necessitates the use of carefully selected materials from which phantoms and radiation ...
openaire +2 more sources
Collaborative Compressive Detection With Physical Layer Secrecy Constraints
This paper considers the problem of detecting a high dimensional signal (not necessarily sparse) based on compressed measurements with physical layer secrecy guarantees. First, we propose a collaborative compressive detection (CCD) framework to compensate for the performance loss due to compression with a single sensor.
Kailkhura, Bhavya +2 more
openaire +2 more sources
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead +4 more
wiley +1 more source
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai +12 more
wiley +1 more source
Phase space compression of a positive muon beam in two spatial dimensions
We present the first demonstration of simultaneous phase space compression in two spatial dimensions of a positive muon beam, the first stage of the novel high-brightness muon beam under development by the muCool collaboration at the Paul Scherrer ...
A. Antognini, N. J. Ayres, I. Belosevic, V. Bondar, A. Eggenberger, M. Hildebrandt, R. Iwai, K. Kirch, A. Knecht, G. Lospalluto, J. Nuber, A. Papa, M. Sakurai, I. Solovyev, D. Taqqu, T. Yan
doaj +1 more source
Numerical investigation of blanking for metal polymer sandwich sheets
Metal polymer sandwich sheets consist of materials with drastically different mechanical properties. Due to this fact and because of high local gradients in the cutting zone during the blanking process, traditional process strategies and empirical ...
Gutknecht Florian +3 more
doaj +1 more source
Financial Distress and Its Determinants in Rheumatoid Arthritis
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler +5 more
wiley +1 more source
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham +29 more
wiley +1 more source

