Results 81 to 90 of about 1,612,001 (340)

Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte, Berta Estévez‐Arias, Leslie Matalonga, Delia Yubero, Anna Codina, Carlos Ortez, Julita Medina, Lidia DeSena DeCabo, Laura Carrera‐García, Jesica Expósito‐Escudero, Cristina Jou, Eduardo F. Tizzano, Andres Nascimento, Daniel Natera‐de Benito   +13 more
wiley   +1 more source

Compression of dynamic tactile information in the human hand

Science Advances, 2020
The mechanics of wave transmission in the human hand effect the preneuronal compression of tactile information. A key problem in the study of the senses is to describe how sense organs extract perceptual information from the physics of the environment ...
Yitian Shao, V. Hayward, Y. Visell
semanticscholar   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Compressive sensing as a paradigm for building physics models [PDF]

Physical Review B, 2013
The widely accepted intuition that the important properties of solids are determined by a few key variables underpins many methods in physics. Though this reductionist paradigm is applicable in many physical problems, its utility can be limited because the intuition for identifying the key variables often does not exist or is difficult to develop ...
Fei Zhou, Vidvuds Ozoliņš, Lance J. Nelson, Gus L. W. Hart   +3 more
openaire   +2 more sources

Direct numerical simulation of supersonic flow and acoustics over a compression ramp

The Physics of Fluids, 2020
We present direct numerical simulations of the shock wave boundary layer interaction (SBLI) at Mach number 2.9 over a 24° ramp. We study both the numerical accuracy and flow physics.
I. Kokkinakis, D. Drikakis, Konstantinos Ritos, S. Spottswood   +3 more
semanticscholar   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Dynamic convergent shock compression initiated by return current in high-intensity laser–solid interactions

Matter and Radiation at Extremes
We investigate the dynamics of convergent shock compression in solid cylindrical targets irradiated by an ultrafast relativistic laser pulse. Our particle-in-cell simulations and coupled hydrodynamic simulations reveal that the compression process is ...
Long Yang, Martin Rehwald, Thomas Kluge, Alejandro Laso Garcia, Toma Toncian, Karl Zeil, Ulrich Schramm, Thomas E. Cowan, Lingen Huang   +8 more
doaj   +1 more source

Transverse compression of an intense ion beam propagating through an alternating-gradient quadrupole lattice

Physical Review Special Topics. Accelerators and Beams, 2006
The transverse compression and dynamics of an intense beam propagating through an alternating-gradient quadrupole lattice, plays an important role in many accelerator physics applications. Typically, the compression can be achieved by means of increasing
Mikhail Dorf, Ronald C. Davidson, Edward A. Startsev   +2 more
doaj   +1 more source

Self-compression at 1 µm wavelength in all-bulk multi-pass geometry

Applied physics B, 2020
We present directly oscillator-driven self-compression inside an all-bulk Herriott-type multi-pass cell in the near-infrared spectral range. By utilizing precise dispersion management of the multi-pass cell mirrors, we achieve pulse compression from 300 ...
Sebastian Gröbmeyer, K. Fritsch, Benedikt Schneider, Markus Poetzlberger, V. Pervak, J. Brons, O. Pronin   +6 more
semanticscholar   +1 more source

Data‐driven forecasting of ship motions in waves using machine learning and dynamic mode decomposition

International Journal of Adaptive Control and Signal Processing, EarlyView.
Summary Data‐driven forecasting of ship motions in waves is investigated through feedforward and recurrent neural networks as well as dynamic mode decomposition. The goal is to predict future ship motion variables based on past data collected on the field, using equation‐free approaches.
Matteo Diez, Mauro Gaggero, Andrea Serani   +2 more
wiley   +1 more source