Numerical simulation of pipe pile composite foundation of deep soft foundation under embankment
Combined with the in-situ test results of the piled embankment with deep soft foundation at the bridge-head of expressway, several axisymmetric finite element numerical modeling methods for single pipe pile in composite foundation are compared and ...
JIANG Yanbin +4 more
doaj +1 more source
The current study presents research investigations and developments related to the homogeneous charge compression ignition (HCCI) engine. Research investigations and recent advances, including the role of various operating conditions on HCCI engine ...
Shyamal Das +7 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Poisson’s ratio of nucleus pulposus tissue : comparison of experimental results with a biphasic poroviscoelastic finite element model [PDF]
This presentation looks at Poisson’s ratio of nucleus pulposus tissue, comparison of experimental results with a biphasic poroviscoelastic finite element ...
Farrell, Mark, Riches, Philip
core +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Spark ignition internal combustion engine efficiency improvement - a variable compression ratio option [PDF]
Pressure to reduce energy consumption is increasing. The problem of vehicle fuel consumption and emissions is approached by exploring various vehicle propulsion options, assessing their net effectiveness on a energy conversion basis and on a usability ...
Malpress, Ray
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Liquid-Flooded Compression and Expansion in Scroll Machines – Part I: Model Development [PDF]
A detailed mechanistic model has been developed for scroll compressors and scroll expanders with liquid flooding for application to the Liquid Flooded Ericsson Cycle.
Groll, Eckhard +7 more
core +2 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source

