KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Patient perspectives: explaining low rates of compliance to compression therapy
Background Although varied interventions are used to prevent venous leg ulcers (VLUs), compression therapy remains the gold standard for VLU prevention and treatment1–3. However, non-compliance remains an issue.
Francisca Chitambira
semanticscholar +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Recommendations for the diagnosis and treatment of chronic venous disease
Clinical manifestations of chronic superficial venous insufficiency are described, followed by recommendations for diagnostic evaluation and various treatment possibilities.
Nada Kecelj Leskovec +8 more
doaj
A Case Report on Theruptor Novo: An Antimicrobial Dressing in the Management of Venous Leg Ulcer [PDF]
Venous Leg Ulcer (VLU) is defined as any break in the skin that has either been present for longer than six weeks or occurs in a person with a history of VLU.
Subhash M Kale
doaj +1 more source
Creating innovation in lymphoedema nursing through collaboration [PDF]
Against a background of fiscal and regulatory pressure to rationalize and justify health-care interventions, there is an underlying political message that greater cooperation and collaboration would improve health-care for all.
Davies, R., Jones, J.
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Ask the expert: How to prevent leg ulcer recurrence when moving into compression hosiery. Leg ulceration [PDF]
Once patients’ leg ulcers are healed, it is recommended that you move them from compression bandaging into leg ulcer hosiery kits or maintenance hosiery.
Atkin, Leanne
core
Case study: obesity, genital oedema and lower limb compression bandaging [PDF]
The purpose of this article is to present an evidenced based rationale for lymphoedema compression bandaging one aspect of treatment for a patient with complex lower limb lymphoedema.
Lister, Lindsey, Noble-Jones, Rhian
core +1 more source
Compression therapy in venous diseases: current forms of compression materials and techniques
Compression therapy (CT) is an established treatment method in chronic venous disease (CVD). The paper presents information on different CT forms with indications and contraindications based on expert consensuses from recent years.
Andrzej Berszakiewicz +4 more
semanticscholar +1 more source

