Results 51 to 60 of about 1,128,000 (254)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

An adaptive approach for integrating primary user behavior in compressive spectrum sensing

EURASIP Journal on Wireless Communications and Networking
Compressive sensing (CS) has been widely used to sense the wideband spectrum with fewer measurements by taking advantage of radio spectrum underutilization.
Ahmed A. Tawfik, Sherif M. Abuelenin, Mohamed F. Abdelkader   +2 more
doaj   +1 more source

Compressive mobile sensing in robotic mapping

, 2009
This paper presents a novel approach, compressive mobile sensing, to use mobile sensors to sample and reconstruct sensing fields based on compressive sensing.
Huang, Shuo, Jindong Tan, Tan, Jindong, Shuo Huang   +3 more
core   +1 more source

Compressive sensing based spatial frequency domain imaging reconstruction

, 2020
Compressive sensing methods demonstrate the ability to collect large data sets using a reduced number of observations. Here we present advantages of compressive sensing applied to Spatial Frequency Domain Imaging.
Spear, Abigail M., Dehghani, Hamid; id_orcid, Mellors, Ben O.L., Howle, Christopher R.   +3 more
core   +1 more source

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High BMI: A Secondary Analysis of the IDEA Trial

Arthritis Care &Research, Accepted Article.
Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck, J. Elyse Borgert, Hyeon Lee, Liubov Arbeeva, Yvonne M. Golightly, Richard F. Loeser, Leigh F. Callahan, Stephen P. Messier, Brian Pietrosimone, Amanda E. Nelson, James S. Marron   +10 more
wiley   +1 more source

The content and reporting completeness of physical therapist‐led interventions for glenohumeral osteoarthritis: a systematic review

Arthritis Care &Research, Accepted Article.
Objectives This study synthesised the content and reporting completeness of published physical therapist‐led interventions for glenohumeral osteoarthritis (GHOA). Methods This systematic review undertook electronic database searches in PubMed, EMBASE, Cochrane, CINAHL and PEDro (until June 2025) for any peer‐reviewed articles/studies describing ...
Daha G Muhammad, Nadine E Foster, Mickylle Pelaez, Karina O'Leary, Ilana N Ackerman, Jonathan G Quicke   +5 more
wiley   +1 more source

Incorporating Primary Occupancy Patterns in Compressive Spectrum Sensing

IEEE Access, 2019
Wideband spectrum sensing remains one of the challenging problems facing the wide deployment of cognitive radio networks. Compressive sensing (CS) was proposed as a promising approach to this problem by utilizing the sparse structure of the underutilized
Omar M. Eltabie, Mohamed F. Abdelkader, Atef M. Ghuniem   +2 more
doaj   +1 more source

DIFFRACTION EFFICIENCY-AWARE RECONSTRUCTION FOR COMPRESSIVE SENSING IN THE MID-INFRARED

, 2023
Compressive sensing has established itself as a novel imaging paradigm. In this paper, we analyze the behavior of a a compressive instrument based on spatial light modulators (SLM), operating in the mid-infrared.
Tiziano Bianchi, Nicola Prette, Donatella Guzzi, Vanni Nardino, Valentina Raimondi, Enrico Magli, Cinzia Lastri, Diego Valsesia, Lorenzo Palombi   +8 more
core