Results 181 to 190 of about 25,437 (265)

AI‐Driven Synthesis in Medicinal Chemistry: Integrating Large Language Models, Robotic Automation, and Sustainability Metrics to Accelerate Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) is transforming synthetic chemistry from task‐specific predictors into integrated platforms that unify retrosynthesis, reaction optimization, and closed‐loop robotic automation. This review highlights how AI‐assisted planning and robotic execution shorten cycle times, reduce step counts, and improve route ...
Amit Gangwal, Antonio Lavecchia
wiley   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Influence of Thermal Cycling on Friction, Wear, and Damage Evolution of Fused Deposition Modeling of 3D‐Printed Glass Fiber Reinforced Polylactic Acid Composites

Polymer Composites, EarlyView.
Schematic illustration of the experimental procedure of the specimens. ABSTRACT This research work investigated the effect of the cyclic thermo‐hygrometric aging regime between −20°C and +40°C with 0–400 cycles on the reciprocating tribological properties of fused deposition modeling (FDM) printed polylactic acid (PLA) and the same material reinforced ...
Sinan Fidan, Satılmış Ürgün, Nevin Gamze Karsli, Taner Yılmaz, Mustafa Özgür Bora, Mehmet İskender Özsoy   +5 more
wiley   +1 more source

Potential of Thermoset Polyolefins for FRP Concrete Reinforcing Bars

Polymer Composites, EarlyView.
Overview of XLPO and pDCPD resins for FRP reinforcing bars, highlighting resin chemistry, key performance characteristics, fiber sizing interactions, and principal degradation mechanisms in concrete environments. ABSTRACT Although thermoset polyolefins offer resistance to hydrolytic degradation and favorable processing characteristics, their potential ...
Osama Omar, Farzaneh Mahmoudi, Leonidas G. Bachas, Francisco De Caso, Brahim Benmokrane, Antonio Nanni   +5 more
wiley   +1 more source

High‐strength composites by thiocracking of high‐polypropylene‐content mixed waste

Polymer International, EarlyView.
Mixed plastic waste made up of polystyrene and polypropylene was reacted with elemental sulfur to give high‐strength composites. Abstract Mixed‐material municipal waste poses a persistent end‐of‐life management challenge because the heterogeneous composition limits efficient separation and recycling. After disposal, mixed‐material waste often fragments
Athira Babu, Rhett C. Smith
wiley   +1 more source

In Situ Curing‐Enabled 3D Printing of Continuous Fiber‐Reinforced Thermosetting Composites

Journal of Polymer Science, EarlyView.
In situ curing‐enabled the 3D printing of continuous fiber/thermoset composites, which were reviewed. Particularly, four types of in situ curing, were discussed, including Radiation‐induced curing, photothermal curing, electrothermal curing, and frontal polymerization. AI‐integrated printing was also analyzed.
Xiaofei Wu, Harrison Hayworth, Shiren Wang   +2 more
wiley   +1 more source

Repeated Pleistocene Permafrost Episodes in the Western Pannonian Basin

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Concerning the study of past periglacial processes, the Pannonian Basin is a key area as it contains the southernmost frost polygons found in Central Europe. The presence or absence of permafrost is still, however, a matter of debate, and data on the timing of frost action are also scarce.
Krisztina Sebe, Ágnes Novothny, Gergely Surányi, Barbara Varga, László Fodor, Gábor Csillag   +5 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Sustainable Utilization and Fire Protection of Wood‐Based Composites in Buildings: Innovations, Challenges, and Future Directions

Sustainable Development, EarlyView.
ABSTRACT The increasing use of wood and wood‐based composites in construction reflects a global shift toward renewable materials that support sustainable development objectives, including carbon reduction and responsible resource use. While wood offers substantial environmental benefits compared to conventional materials such as concrete and steel, its
Qaisar Munir, Marko Hyvärinen, Timo Kärki   +2 more
wiley   +1 more source

Quality Improvement and the UNSDGs: Mapping Industry Contributions at the Goal, Target and Indicator Levels

Sustainable Development, EarlyView.
ABSTRACT The study examines the extent to which industry‐led quality improvement projects contribute to the United Nations Sustainable Development Goals (UNSDGs). The objective is to map these contributions to the UNSDGs, targets and indicators to provide a detailed understanding of sustainability alignment through quality management (QM) projects.
Shreeranga Bhat, Jiju Antony, Michael Sony, Anders Fundin, Arshia Kaul, Lars Sörqvist, Raúl Molteni, Sunil Sinha   +7 more
wiley   +1 more source