Results 31 to 40 of about 238,845 (361)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

A State-Supervised Model and Novel Anomaly Index for Gas Turbines Blade Fault Detection Under Multi-Operating Conditions

open access: yesIEEE Access
To meet industrial demands, gas turbines typically operate under multiple conditions, presenting unique challenges for fault diagnosis. This paper proposes a novel blade fault detection framework designed for such environments.
Yuan Xiao   +4 more
doaj   +1 more source

The Effect of the Isolator Design on the Efficiency of Rotary Piston Compressors

open access: yesThermo, 2023
The current work investigates the relationship between the shape of an isolator of a concentric rotary piston compressor and the secondary peak pressure developed during each operating cycle. This peak pressure is developed when the piston passes through
Savvas Savvakis   +2 more
doaj   +1 more source

Active clearance control system for a turbomachine [PDF]

open access: yes, 1982
An axial compressor is provided with a cooling air manifold surrounding a portion of the shroud, and means for bleeding air from the compressor to the manifold for selectively flowing it in a modulating manner axially along the outer side of the stator ...
Coulson, C. E.   +2 more
core   +1 more source

Effects of Non‐Aspirin Nonsteroidal Anti‐Inflammatory Drugs on Acute Intracerebral Hemorrhage

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite celecoxib, a cyclooxygenase‐2 inhibitor, promoting functional recovery from intracerebral hemorrhage (ICH) by reducing inflammation‐mediated perihematomal edema in rat models, the evidence of its effects on patient outcomes remains limited.
Shin‐Joe Yeh   +3 more
wiley   +1 more source

Design of a Steady-State Adjustment Method and Sensitivity Analysis for an ORC System with Plate Heat Exchangers

open access: yesApplied Sciences
Because of its low concentration and low energy in an organic Rankine cycle (ORC) system, more than 50% of low-grade thermal energy with a temperature below 300 °C is not taken seriously.
Lantian Ji   +3 more
doaj   +1 more source

Two-stage coaxial gas compressor [PDF]

open access: yes, 1972
Compressor raises pressure of gases from low ambient supply during space experiments by a system of low weight, size, and power input. Dc rotary-torque motor and ball-screw drive shaft activate first and second stage of compressor, utilizing inertia ...
Huniu, S.   +2 more
core   +1 more source

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