Results 81 to 90 of about 176,574 (301)

Calcium-Channel Antagonists Inhibit Marble-Burying Behavior in Mice

Journal of Pharmacological Sciences, 2008
In the present study, we examined the effects of calcium-channel antagonists on marble-burying behavior, which is an animal model of obsessive-compulsive disorder. Amlodipine (10 mg/kg, i.p.), cilnidipine (10 mg/kg, i.p.), nilvadipine (3 and10 mg/kg, i.p.
Nobuaki Egashira, Ryoko Okuno, Moe Abe, Michihiko Matsushita, Kenichi Mishima, Katsunori Iwasaki, Ryozo Oishi, Ryoji Nishimura, Yoshiaki Matsumoto, Michihiro Fujiwara   +9 more
doaj   +1 more source

Rise of Mental Sub-Health Consumers: Examining the Compulsive Buying Behavior in the Post-COVID-19 Era

SAGE Open, 2023
The aftermath of the pandemic may have changes in consumer behaviors and motivations for buying. This study aims to find and prove the underlying psychological factors of compulsive buying behavior under the conditions of social isolation. The structural
Fei Huang, Wenqiu Guo
doaj   +1 more source

\u3cem\u3eN\u3c/em\u3e-acetylcysteine Decreases Binge Eating in a Rodent Model [PDF]

, 2016
Binge-eating behavior involves rapid consumption of highly palatable foods leading to increased weight gain. Feeding in binge disorders resembles other compulsive behaviors, many of which are responsive to N-acetylcysteine (NAC), which is a cysteine ...
Baker, David A., Choi, Sujean, Frenkel, M. M., Hurley, M. M., Maunze, Brian, Resch, Jon M.   +5 more
core   +1 more source

Whole-genome association analysis of treatment response in obsessive-compulsive disorder. [PDF]

, 2016
Up to 30% of patients with obsessive-compulsive disorder (OCD) exhibit an inadequate response to serotonin reuptake inhibitors (SRIs). To date, genetic predictors of OCD treatment response have not been systematically investigated using genome-wide ...
Askland, KD, Bienvenu, OJ, Cullen, BA, Fyer, AJ, Geller, D, Goes, FS, Grados, MA, Greenberg, BD, Knowles, JA, Lange, C, Liang, K-Y, Maher, B, Mattheisen, M, McCracken, JT, McLaughlin, NC, Murphy, DL, Nestadt, G, Nurmi, EL, Pauls, D, Piacentini, J, Pulver, AE, Qin, H, Rasmussen, SA, Riddle, MA, Samuels, JF, Shugart, YY, Stewart, SE, Valle, D, Wang, Y, Zhu, Y   +29 more
core   +2 more sources

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Pain and Problem Behavior in Cats and Dogs

Animals, 2020
We argue that there is currently an under-reporting of the ways in which pain can be associated with problem behavior, which is seriously limiting the recognition of this welfare problem.
Daniel S. Mills, Isabelle Demontigny-Bédard, Margaret Gruen, Mary P. Klinck, Kevin J. McPeake, Ana Maria Barcelos, Lynn Hewison, Himara Van Haevermaet, Sagi Denenberg, Hagar Hauser, Colleen Koch, Kelly Ballantyne, Colleen Wilson, Chirantana V Mathkari, Julia Pounder, Elena Garcia, Patrícia Darder, Jaume Fatjó, Emily Levine   +18 more
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

The Relationship Between Alexithymia And Compulsive Shopping Among Young Adults

Academic Journal of Psychology and Counseling
Although previous studies have investigated factors contributing to compulsive shopping, the specific role of alexithymia and its influence on emotional regulation in predicting this behavior remains underexplored.
Martina Barbera, Amelia Rizzo
doaj   +1 more source

Robot Models of Mental Disorders [PDF]

, 2017
Alongside technological tools to support wellbeing and treatment of mental disorders, models of these disorders can also be invaluable tools to understand, support and improve these conditions.
Cañamero, Lola, Lewis, Matthew
core   +2 more sources

From Custom to Court: The Evolution of Mediation in European Legal Systems

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article traces how European mediation has repeatedly rebalanced three variables—(1) the source of mediator authority, (2) the degree of institutionalization, and (3) the operative meaning of voluntariness—from antiquity to the present. Using three periods—Proto‐Mediation (c. 500 BCE–c. 1750), Classical Mediation (c.
Viktoriia Hamaiunova
wiley   +1 more source