Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano +33 more
wiley +1 more source
Transdiagnostic Compulsivity Traits in Problematic Use of the Internet Among UK Residents: Cross-Sectional Network Analysis Study. [PDF]
Liu C +10 more
europepmc +1 more source
Clinical Predictors of Tic‐Related Impairment in Children and Adults with Tourette Syndrome
Abstract Background Tic‐related impairment drives treatment decisions for Tourette syndrome and related tic disorders. The clinical features most strongly associated with impairment remain unclear. Objective The aim of this analysis is to identify clinical predictors of tic‐related impairment in children and adults with tic disorders in a prospective ...
Wm. Jeptha Davenport +4 more
wiley +1 more source
Seeking Satisfaction Among Israeli Young Adults: The Roles of Gratification, Compensation, Reward Deficiency Syndrome, and Compulsivity in Relation to Addictive Behaviors. [PDF]
Efrati Y +7 more
europepmc +1 more source
This scoping review of 33 studies maps the landscape of mental health in persons with physical disabilities. It finds a high prevalence of depression, anxiety, posttraumatic stress disorder, and other psychological problems, but highlights significant heterogeneity across studies in sample size, measurement, and representativeness.
Hui Li +7 more
wiley +1 more source
Advancing translational research in binge-eating: Integrating insights from clinical practice into animal models. [PDF]
Dufour R, Shalev U, Booij L.
europepmc +1 more source
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
Recent advances in understanding how compulsivity is related to behavioural addictions over their timecourse. [PDF]
Solly JE +5 more
europepmc +1 more source
Factors Associated with Early Discontinuation of Foslevodopa/Foscarbidopa in Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.
Keita Kakuda +7 more
wiley +1 more source

