Results 91 to 100 of about 161,995 (304)
The Amended Canadian Patent Act: General Amendments and Pharmaceutical Patents Compulsory Licensing Provisions [PDF]
, 1987 On November 19, 1987, the Canadian Senate gave final approval to a number of far-reaching and controversial amendments to the Canadian Patent Act ( Amending Act ).
Chromecek, Milan
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FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Research and Reports in Tropical Medicine, 2012 Michael W Miller1, Richard Tren21Duke Global Health Institute, Duke University, Durham, NC, USA; 2Africa Fighting Malaria, Washington, DC, USAAbstract: Millions of people rely on public-health insecticides for malaria prevention.
Miller MW, Tren R
doaj
Stay Tuned: Whether Cloud-Based Service Providers Can Have Their Copyrighted Cake and Eat It Too [PDF]
, 2014 Copyright owners have the exclusive right to perform their works publicly and the ability to license their work to others who want to share that right. Subsections 106(4) and (5) of the Copyright Act govern this exclusive public performance right, but
Asaro, Amanda
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Interests Analysis on Compulsory License
Beijing Law Review, 2016 In this paper I turn to different conceptions of interest. There are several theories in the field of political philosophy about what interest is and therefore several conceptions of interest exist. Three pairs of interest are clarified: interest as welfare and interest as resource, reflective interest and volitional interest, public interest and ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
An Overview and Comparison of Aviation and Space Insurance [PDF]
, 2019 Commercial aviation and commercial space operations entail significant risk. The very nature of these operations means a mishap can result in significant financial losses.
Suchodolski, Jeanne
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