Results 41 to 50 of about 161,995 (304)

Frand v. Compulsory Licensing: The Lesser of the Two Evils [PDF]

open access: yes, 2015
This paper focuses on two types of licenses that can best be described as outliers—FRAND and compulsory licenses. Overall, these two specific forms of licenses share the objective of producing a fair and reasonable license of a technology protected by ...
Davé, Raj   +2 more
core   +2 more sources

Assertive modesty: an economics of intangibles [PDF]

open access: yes, 1994
At the center of our Symposium stand two papers: A Manifesto Concerning the Legal Protection of Computer Programs (Manifesto) and Legal Hybrids: Between the Patent and Copyright Paradigms (Legal Hybrids). Both are stimulating. Both are lengthy.
Gordon, Wendy J.
core   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

EKSISTENSI “THE TRIPS SAFEGUARDS” DI DALAM PERJANJIAN TRIPS: DALAM PERSPEKTIF KESEHATAN MASYARAKAT

open access: yesMimbar Hukum, 2008
Developing countries believe that the TRIPS Agreement gives more benefits to pharmaceutical companies of developed countries and prevents access to cheaper and affordable drugs. A reduction of drug prices has occurred when developing countries applied
Tomi Suryo Utomo
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Current Problems of International Legal Copyright Protection

open access: yesТеоретическая и прикладная юриспруденция
The article examines the level of international copyright protection from the perspective of such aspects as the urgent nature of copyright protection and the possibility of applying the institution of compulsory license.
L. V. Shvarts, S. M. Burova
doaj   +1 more source

Canada's implementation of the Paragraph 6 Decision: is it sustainable public policy?

open access: yesGlobalization and Health, 2007
Background Following the Implementation of Paragraph 6 of the Doha Declaration on TRIPS and Public Health, Canada was among the first countries globally to amend its patent law, which resulted in Canada's Access to Medicines Regime (CAMR).
Cosio Andre   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

BATAS KEWENANGAN PENYIDIK PEGAWAI NEGERI SIPIL DAN KEPOLISIAN DALAM PENINDAKAN PELANGGARAN LALU LINTAS DAN ANGKUTAN JALAN

open access: yesJurnal Magister Hukum Udayana, 2013
The State of Indonesia is a state of the rule of law (rechtstaat) based on Pancasila. As a state based on law, Traffic and Road Transportation under Law No.
Putu Yuni Riswanty
doaj   +1 more source

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