Results 71 to 80 of about 161,995 (304)

Brief of Law Professors as Amicus Curiae in Support of Respondent [PDF]

open access: yes, 2003
Inventors lacking assurance of a market, or even the right to practice patented inventions, face considerable risk. Those who qualify for patents, in return for disclosure, receive only the assistance of the courts in excluding others from economic ...
Field, Thomas G., Jr   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Editorial

open access: yesCondensed Matter Physics, 2020
Dear readers, We would like to thank you for being with us, both as readers and contributors to Condensed Matter Physics. Our special thanks are given to the referees for their time-consuming and noble efforts towards thorough reviewing the submitted ...
Editorial Board
doaj   +1 more source

TRIPS, eBay, and Denials of Injunctive Relief: Is Article 31 Compliance Everything? [PDF]

open access: yes, 2009
In eBay, Inc. v. MercExchange, L.L.C., the Supreme Court held that decisions to grant injunctive relief must accord with the traditional principles of equity, thereby invalidating the practice of generally granting permanent injunctions to patentees upon
Mace, Andrew C.
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Flexibilities under Trips: Implementation Gaps between Theory and Practice

open access: yesNordic Journal of Commercial Law, 2013
Agreement on Trade Related Aspects of Intellectual Property (hereinafter TRIPS) aimed at fostering innovation and developing a system based on innovation-oriented national economies.
Muhammad Zaheer Abbas, Shamreeza Riaz
doaj   +2 more sources

Zadania inwestycyjne jednostek samorządu terytorialnego województwa lubelskiego w zakresie ochrony zdrowia = Investment projects of local government units in the province of Lublin about health care

open access: yesJournal of Education, Health and Sport, 2016
Warchoł Martyna, Furtak-Niczyporuk Marzena, Pachuta Małgorzata. Zadania inwestycyjne jednostek samorządu terytorialnego województwa lubelskiego w zakresie ochrony zdrowia = Investment projects of local government units in the province of Lublin about ...
Martyna Warchoł   +2 more
doaj   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Korea, the Pharmaceutical Industry and Non-Commercial Use in the TRIPS Agreement [PDF]

open access: yes
In 2002, a number of associations requested the Korean Patent Office to issue a compulsory license for the manufacture of a drug under the Korean patent provision which permits the issue of compulsory licensing for public non-commercial use.
Shanker, Daya
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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