Results 31 to 40 of about 461,649 (298)
Computational models for parallel computers [PDF]
Philosophical Transactions of the Royal Society of London. Series A, Mathematical and Physical Sciences, 1988 Computational models define the usage patterns of a computer. They can be used to derive the architecture of the machine, provide guidelines for programming tools, and suggest how the machine should be used in applications. Identifying computational models is especially important for parallel computers, because their architectures and usages are still ...
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From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Applied Mathematics and Computation, 2009 In this survey we consider optical computers that encode data using images and compute by transforming such images. We give an overview of a number of such optical computing architectures, including descriptions of the type of hardware commonly used in optical computing, as well as some of the computational efficiencies of optical devices.
Woods, Damien, Naughton, Thomas J.
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A Complete Theory of Everything (Will Be Subjective)
Algorithms, 2010 Increasingly encompassing models have been suggested for our world. Theories range from generally accepted to increasingly speculative to apparently bogus.
Marcus Hutter
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Weihrauch-completeness for layerwise computability [PDF]
Logical Methods in Computer Science, 2018 We introduce the notion of being Weihrauch-complete for layerwise computability and provide several natural examples related to complex oscillations, the law of the iterated logarithm and Birkhoff's theorem. We also consider hitting time operators, which
Arno Pauly, Willem Fouché, George Davie
doaj +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
On Accelerations in Science Driven by Daring Ideas: Good Messages from Fallibilistic Rationalism
Studies in Logic, Grammar and Rhetoric, 2015 The first good message is to the effect that people possess reason as a source of intellectual insights, not available to the senses, as e.g. axioms of arithmetic. The awareness of this fact is called rationalism.
Marciszewski Witold
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Frontiers in Psychology, 2014 It is a truism that conceptual understanding of a hypothesis is required for its empirical investigation. However the concept of recursion as articulated in the context of linguistic analysis has been perennially confused.
Jeffrey eWatumull +4 more
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Closed Sets and Operators thereon: Representations, Computability and Complexity [PDF]
Logical Methods in Computer Science, 2018 The TTE approach to Computable Analysis is the study of so-called representations (encodings for continuous objects such as reals, functions, and sets) with respect to the notions of computability they induce.
Carsten Rösnick-Neugebauer
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