Results 121 to 130 of about 120,189 (290)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Absolute exponential stability of switching time-delay Lurie systems with the application to switching Hopfield neural networks

Nonlinear Analysis
This paper investigates the problem of absolute exponential stability analysis for switching time-delay Lurie system (STDLS) with all modes unstable.
Wenxiu Wenxiu Zhao, Yuangong Sun
doaj   +1 more source

Tariffs in New Zealand : The economic impacts of retaining tariffs in New Zealand A dynamic CGE analysis [PDF]

The government announced in late 2009 that it would freeze tariffs at current levels until 2015 at the earliest. We examine the potential costs and benefits to the New Zealand economy of this policy decision using a recently-developed dynamic computable ...
James Giesecke, James Zuccollo, John Ballingall   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Preface to Computer algebra and computer analysis

Journal of Symbolic Computation, 2003
Wolfram Koepf, Karin Gatermann
openaire   +1 more source

Proof theory and computational analysis

Electronic Notes in Theoretical Computer Science, 1997
In this survey paper we start with a discussion how functionals of finite type can be used for the proof-theoretic extraction of numerical data (e.g. effective<br />uniform bounds and rates of convergence) from non-constructive proofs in numerical analysis.
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Electronic Health Records for Population Health Management: Comparison of Electronic Health Record–Derived Hypertension Prevalence Measures Against Established Survey Data

Online Journal of Public Health Informatics
BackgroundHypertension is the most prevalent risk factor for mortality globally. Uncontrolled hypertension is associated with excess morbidity and mortality, and nearly one-half of individuals with hypertension do not have the ...
Katie S Allen, Nimish Valvi, P Joseph Gibson, Timothy McFarlane, Brian E Dixon   +4 more
doaj   +1 more source

Energy market liberalisation in the FSU - simulations with the GTAP model [PDF]

This work considers effects of energy market liberalisation in the countries of the former Soviet Union (FSU). Our analysis is based on a computable general equilibrium (CGE) model called the Global Trade Analysis Project (GTAP).
Toni Riipinen
core