Results 31 to 40 of about 2,172 (262)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Current Tracking Adaptive Control of Brushless DC Motors
International Journal of Adaptive Control and Signal Processing, EarlyView.In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García +3 more
wiley +1 more source
THE IMPACT ASSESSMENT OF AN EVENTUAL OIL PRICE SHOCK WITH A COMPUTABLE GENERAL EQUILIBRIUM MODEL
Revue des Etudes Multidisciplinaires en Sciences Economiques et Sociales, 2021 Energy issues are taking an increasingly important place in the various global agendas and there is no longer any doubt that the competition on energy will have repercussions all over the world.
Fouad ELAME, Hayat LIONBOUI
doaj +1 more source
MaCGE-MOD: Malta’s Computable General Equilibrium Model
SSRN Electronic JournalThis paper introduces the latest addition to the modelling toolkit of the Central Bank of Malta: a static Computable General Equilibrium model for Malta named MaCGE-MOD. Developed through a collaboration with the University of Macerata, the model is a multiinput, multi-output and multi-sector model, calibrated on a Social Accounting Matrix which ...
Ian P. Cassar +6 more
openaire +3 more sources
Fuel Subsidies in Ecuador: A Computable General Equilibrium Model for Targeting Evaluation
Latin American Research ReviewFuel subsidies have been an enduring policy in Ecuador’s political and economic history. Given their lack of targeting and high opportunity cost, they have been amply criticized.
Cristhian Montenegro-Casa +1 more
doaj +1 more source
Lowering CO2 emissions in the Swiss transport sector
Swiss Journal of Economics and Statistics, 2019 In Switzerland, transportation represents 41% of CO2 emissions from energy combustion (2016), a much higher share than in the European Union (EU) (28%) or even the USA (34%).
Philippe Thalmann, Marc Vielle
doaj +1 more source