Results 31 to 40 of about 2,240 (262)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Analysis of Environmental and Welfare Effects of Energy Subsidy Refor Application of Computable General Equilibrium Model [PDF]

open access: yesPizhūhishnāmah-i Iqtiṣād-i Inirzhī-i Īrān, 2015
The second step of subsidies targeting program which is coupled with energy price reform, has multiple effects on the economy. One of the major effects is the welfare and environmental changes in the country.
Hamid Amadeh   +2 more
doaj  

THE IMPACT ASSESSMENT OF AN EVENTUAL OIL PRICE SHOCK WITH A COMPUTABLE GENERAL EQUILIBRIUM MODEL

open access: yesRevue des Etudes Multidisciplinaires en Sciences Economiques et Sociales, 2021
Energy issues are taking an increasingly important place in the various global agendas and there is no longer any doubt that the competition on energy will have repercussions all over the world.
Fouad ELAME, Hayat LIONBOUI
doaj   +1 more source

Is 'WTO-Plus' a Policy Option for India-China Agriculture Trade? A CGE Analysis [PDF]

open access: yesEurasian Journal of Business and Economics, 2020
This paper examines the effect of bilateral tariff reduction in the agriculture sector between India and China. The results are evaluated in terms of welfare, output, employment and the potential trade flows between India and China using the GTAPmodel.
Shahid AHMED, Saba ISMAIL
doaj   +1 more source

THE CONCEPT OF COMPUTABLE GENERAL EQUILIBRIUM MODELS

open access: yesInternational Journal of Research in Commerce and Management Studies, 2022
This paper contributes to the existing literature on the general concept on use of the Computable general equilibrium (CGE) models of importance in developing processes. Computable general equilibrium (CGE) models are used widely in policy analysis, especially in developed-country academic settings and also for the purpose of sharing these lessons with
Ernest Simeon O. Odior, Sabastine Arinze
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Economic Impacts of Thailand’s Biofuel Subsidy Reallocation Using a Dynamic Computable General Equilibrium (CGE) Model

open access: yesEnergies, 2021
For two decades, the Thai government has been promoting ethanol and biodiesel consumption through tax measures and price subsidies. Although this policy has substantially increased the consumption and production of biofuels, there is concern regarding ...
Korrakot Phomsoda   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Fuel Subsidies in Ecuador: A Computable General Equilibrium Model for Targeting Evaluation

open access: yesLatin American Research Review
Fuel subsidies have been an enduring policy in Ecuador’s political and economic history. Given their lack of targeting and high opportunity cost, they have been amply criticized.
Cristhian Montenegro-Casa   +1 more
doaj   +1 more source

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