Results 51 to 60 of about 74,556 (151)

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

open access: yesEpilepsia, Volume 67, Issue 6, Page 3185-3198, June 2026.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo   +7 more
wiley   +1 more source

Aspiraciones y fracasos de una escuela-computador. Escuela de Arquitectura de la Universidad de Costa Rica, 1971-1979

open access: yesDearq, 2020
Este artículo examina críticamente discursos y prácticas pedagógicas desarrollados en la Escuela de Arquitectura de la Universidad de Costa Rica a partir de 1971, mostrando cómo principios derivados de las ciencias de la computación sirvieron para ...
Natalia Solano Meza
doaj   +1 more source

From Stability to Chaos: A Complete Classification of the Damped Klein‐Gordon Dynamics

open access: yesMathematical Methods in the Applied Sciences, Volume 49, Issue 9, Page 9696-9708, June 2026.
ABSTRACT We investigate the transition between stability and chaos in the damped Klein‐Gordon equation, a fundamental model for wave propagation and energy dissipation. Using semigroup methods and spectral criteria, we derive explicit thresholds that determine when the system exhibits asymptotic stability and when it displays strong chaotic dynamics ...
Carlos Lizama   +2 more
wiley   +1 more source

Editorial

open access: yesRevista Colombiana de Computación, 2019
La Universidad Autónoma de Bucaramanga Unab y los miembros del Comité Editorial de la Revista Colombiana de Computación, se complacen en presentar esta nueva edición de la Revista con un total de cinco artículos.
Diana Teresa Parra Sánchez
doaj   +1 more source

Factors to Foster Resilience Against Coding Stressors of Agile Software Developers

open access: yesJournal of Software: Evolution and Process, Volume 38, Issue 6, June 2026.
ABSTRACT IT workers, especially software developers, undergo high stress levels due to their intellectual activity, which requires creativity and problem‐solving skills for specific situations. These circumstances often lead to a fast‐paced lifestyle, including sleep deprivation, which is often worn as a badge of honor.
Ramón R. Palacio   +4 more
wiley   +1 more source

System of didactic procedures to drive the teaching-learning of the computation in the half school level

open access: yesMaestro y Sociedad, 2016
A system of teaching methods is presented to drive the dynamics of the teaching-learning process of the Computation in the Half School Level, based on an interdisciplinary logic from cognitive nodes.
Isabel Alonso-Berenguer   +2 more
doaj  

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro   +5 more
wiley   +1 more source

Computación de altas prestaciones ecológica [PDF]

open access: yes, 2012
La computación de altas prestaciones ha tenido, por décadas, el único objetivo de incrementar la velocidad de procesamiento de las aplicaciones computacionalmente complejas.
Uribe, Federico   +3 more
core  

N-gramas sintácticos y su uso en la lingüistica computacional [PDF]

open access: yesRevista Vectores de Investigación, 2013
En este artículo, estamos introduciendo un nuevo concepto que se utilizará en la lingüística computacional, se llama n-gramas sintácticos: son n-gramas que se construyen siguiendo un árbol sintáctico. Es equivalente a introducir la información sintáctica
Grigori Sidorov
doaj  

Observational Uncertainty in Deep Learning Climate Downscaling and Projections

open access: yesEarth and Space Science, Volume 13, Issue 6, June 2026.
Abstract Deep learning (DL) models are increasingly used for climate downscaling, yet the impact of observational uncertainty on their performance remains poorly understood. Here we assess this effect by training ensembles of DL downscaling models using four independent gridded observational data sets over continental Spain that differ in source ...
Samuel Reyes‐Elgueta   +4 more
wiley   +1 more source

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