Results 101 to 110 of about 941,214 (304)
Journal of Traffic and Transportation Engineering (English Edition), 2019 In a previous paper “to retrofit or not to retrofit?” (Nuti and Vanzi, 2003) a straightforward procedure able to forecast the economic return of seismic structural upgrading was presented. More recently, the authors realized that the final mathematical results can be much simplified so as to allow back-of-an-envelope computation.
Fiore A. +5 more
openaire +6 more sources
This is the first ever doctoral thesis in the field of DNA computation. The field has its roots in the late 1950s, when the Nobel laureate Richard Feynman first introduced the concept of computing at a molecular level. Feynman's visionary idea was only
Amos, Martyn
core
Rigorous computation of the endomorphism ring of a Jacobian [PDF]
, 2018 We describe several improvements to algorithms for the rigorous computation of the endomorphism ring of the Jacobian of a curve defined over a number ...
Mascot, Nicolas +4 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An evolutionary algorithm for bilevel optimisation of men's team pursuit track cycling
, 2012 Evolutionary Computation is useful in a broad range of practical applications, however currently generalized algorithms tend to be focused upon solving problems in a theoretical domain. We aim to develop a range of generalised algorithms more suited than
Trent Kroeger +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi DergisiEstablished in Turkey in 1994, the Competition Authority plays a key role in safeguarding and promoting competition in markets. Its main tasks include monitoring agreements, detecting collusive practices and preventing the formation of cartels, as well ...
Murat Aydın, Mehmet Niyazi Çankaya
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
TechnophanyBy ingesting a vast corpus of source material, generative deep learning models are capable of encoding multi-modal data into a shared embedding space, producing synthetic outputs which cannot be decomposed into their constituent parts.
Anil Bawa-Cavia
doaj +1 more source