Results 131 to 140 of about 5,819,802 (336)

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

Attention stabilizes the shared gain of V4 populations

open access: yeseLife, 2015
Responses of sensory neurons represent stimulus information, but are also influenced by internal state. For example, when monkeys direct their attention to a visual stimulus, the response gain of specific subsets of neurons in visual cortex changes. Here,
Neil C Rabinowitz   +3 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Research at CCT (2019) [PDF]

open access: yes, 2019
https://repository.lsu.edu/components/1010/thumbnail ...
LSU Center for Computation and Technology
core   +1 more source

Device-independent test of causal order and relations to fixed-points

open access: yesNew Journal of Physics, 2016
Bell non-local correlations cannot be naturally explained in a fixed causal structure. This serves as a motivation for considering models where no global assumption is made beyond logical consistency.
Ämin Baumeler, Stefan Wolf
doaj   +1 more source

Prospective Algorithms for Quantum Evolutionary Computation [PDF]

open access: yesarXiv, 2008
This effort examines the intersection of the emerging field of quantum computing and the more established field of evolutionary computation. The goal is to understand what benefits quantum computing might offer to computational intelligence and how computational intelligence paradigms might be implemented as quantum programs to be run on a future ...
arxiv  

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