Results 131 to 140 of about 941,214 (304)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Back to the roots : multi-X evolutionary computation
Over the years, evolutionary computation has come to be recognized as one of the leading algorithmic paradigms in the arena of global black box optimization.
Gupta, Abhishek, Ong, Yew-Soon
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Purpose - The language load within mathematics test items can lead to inaccuracy in assessing Orang Asli pupils’ mathematical ability due to their struggle in comprehending the academic language.
Arsaythamby Veloo +2 more
doaj +1 more source
Illustrating evolutionary computation with Mathematica /
An essential capacity of intelligence is the ability to learn. An artificially intelligent system that could learn would not have to be programmed for every eventuality; it could adapt to its changing environment and conditions just as biological systems
Jacob, Christian.
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Using Fast Matrix Multiplication in Bio-Inspired Computation for Complex Optimization Problems
Population-based search heuristics such as evolutionary algorithms or ant colony optimization have been widely used to tackle complex problems in combinatorial optimization.
Florian Diedrich +3 more
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Our Vision for JGR: Machine Learning and Computation
This editorial introduces the inaugural issue of the Journal of Geophysical Research: Machine Learning and Computation to the scientific community, elucidating the motivations and vision behind its establishment.
E. Camporeale +2 more
doaj +1 more source

