Results 211 to 220 of about 380,952 (268)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Leveraging particle dynamics in force-fields for network packet routing. [PDF]

PLoS One
Biswas S, Yang Y, Bhuyan AK, Dutta H, Datta S.   +4 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Phase-independent wireless data aggregation via optical in-sensor computing. [PDF]

Nat Commun
Sun S, Lu Z, Wang Y, Liu Z, Mao Z, Shi Q, Wang F, Wang W, Jiang J, Lu B, He H, Pan X, Qian H, Ye Z.   +13 more
europepmc   +1 more source

In-Memory Bayesian Machine Using Vertical Cu0.33Te0.67/HfO2/TiN Memristive Crossbar Arrays. [PDF]

ACS Nano
Baek IK, Cheong S, Kim HW, Cho JM, Son K, Kim YR, Woo KS, Park H, Kim BS, Hwang CS.   +9 more
europepmc   +1 more source

TCCA: An Inter-Layer Spatiotemporal Cross-Attention Network for IIoT Attack Traffic Detection. [PDF]

Sensors (Basel)
Sun X, Xu B.
europepmc   +1 more source

Modeling process instability in anaerobic digestion by using a thermodynamically corrected model. [PDF]

Front Bioeng Biotechnol
Wittum R, Naegel A, Wittum G.
europepmc   +1 more source

An Outline of New Approach to Computation with Z-Numbers Based on the Concept of Lower Prevision. [PDF]

Entropy (Basel)
Aliev R, Huseynov O, Nuriyev A.
europepmc   +1 more source

Tau positron emission tomography harmonization using the CenTauR approach: General conversion equations, relevant cut-points, and external validation. [PDF]

Alzheimers Dement
Moscoso Rial A, Leuzy A, Raket LL, Villemagne VL, Klein G, Tonietto M, Olafson E, Smith R, Schwarz CG, Baker S, Saad ZS, Bullich S, Lopresti B, Sanabria Bohorquez S, Domingues Kolinger G, Lutz O, Boada M, Betthauser TJ, Charil A, Collins EC, Collins JA, Gunn RN, Higuchi M, Hostetler E, Hutchison RM, Iaccarino L, Insel PS, Irizarry MC, Jack CR, Jagust WJ, Johnson KA, Johnson SC, Tissot C, Vállez García D, Salvadó G, Stephenson D, Marquié M, Mathotaarachchi S, Mintun MA, Ossenkoppele R, Huang Q, Mao X, Gnörich J, Pappas I, Petersen RC, Chiotis K, Rabinovici GD, Rosa-Neto P, Stephens AW, Whittington A, Carrillo MC, Pontecorvo MJ, Budd Haeberlein S, Dunn B, Kolb HC, Tatton N, Karten Y, Brendel M, O'Bryant S, Xie F, Rowe CC, Hansson O, Doré V, Alzheimer's Disease Neuroimaging Initiative (ADNI), Health and Aging Brain Study (HABS‐HD) Study Team.   +64 more
europepmc   +1 more source