Results 71 to 80 of about 5,445,104 (308)

A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection

Toxins, 2017
Developing drugs to treat the toxic effects of lethal toxin (LT) and edema toxin (ET) produced by B. anthracis is of global interest. We utilized a computational approach to score 474 drugs/compounds for their ability to reverse the toxic effects of ...
Jane P. F. Bai, Theodore Sakellaropoulos, Leonidas G. Alexopoulos   +2 more
doaj   +1 more source

Joint Computation and Communication Cooperation for Mobile Edge Computing

, 2017
This paper proposes a novel joint computation and communication cooperation approach in mobile edge computing (MEC) systems, which enables user cooperation in both computation and communication for improving the MEC performance.
Cao, Xiaowen, Cui, Shuguang, Wang, Feng, Xu, Jie, Zhang, Rui   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

SoK: Delegated Security in the Internet of Things

Future Internet
The increased use of electronic devices in the Internet of Things (IoT) leads not only to an improved comfort of living but also to an increased risk of attacks. IoT security has thus become an important research field.
Emiliia Geloczi, Felix Klement, Patrick Struck, Stefan Katzenbeisser   +3 more
doaj   +1 more source

Computing Networks: A General Framework to Contrast Neural and Swarm Cognitions

Paladyn, 2010
This paper presents the Computing Networks (CNs) framework. CNs are used to generalize neural and swarm architectures. Artificial neural networks, ant colony optimization, particle swarm optimization, and realistic biological models are used as examples ...
Gershenson Carlos
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Our Vision for JGR: Machine Learning and Computation

Journal of Geophysical Research: Machine Learning and Computation
This editorial introduces the inaugural issue of the Journal of Geophysical Research: Machine Learning and Computation to the scientific community, elucidating the motivations and vision behind its establishment.
E. Camporeale, R. Marino, the Editorial Board   +2 more
doaj   +1 more source

When Quantum Computation Meets Data Science: Making Data Science Quantum [PDF]

, 2022
Yazhen Wang
openalex   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Regioselective carbon–carbon bond formation of 5,5,5-trifluoro-1-phenylpent-3-en-1-yne

Beilstein Journal of Organic Chemistry, 2013
The regioselective carbon–carbon bond formation was studied using 5,5,5-trifluoro-1-phenylpent-3-en-1-yne as a model substrate, and predominant acceptance of electrophiles β to a CF3 group as well as a deuterium trap experiment of the lithiated species ...
Motoki Naka, Tomoko Kawasaki-Takasuka, Takashi Yamazaki   +2 more
doaj   +1 more source