Results 121 to 130 of about 138,161 (315)

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

open access: yesAdvanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen   +11 more
wiley   +1 more source

Molecular Realization of a Quantum NAND Tree

open access: yes, 2018
The negative-AND (NAND) gate is universal for classical computation making it an important target for development. A seminal quantum computing algorithm by Farhi, Goldstone and Gutmann has demonstrated its realization by means of quantum scattering ...
Aspuru-Guzik, Alán   +4 more
core   +1 more source

Hierarchical Embedded Sphere Model: An Interpretable ML‐Guided Multiscale Descriptor Engineering Decodes OER Activity on TM@MO2 Catalysts

open access: yesAdvanced Science, EarlyView.
Hierarchical Embedded Sphere Model combines DFT and interpretable machine learning to decode catalytic activity on TM‐doped MO2. It disentangles global electronic, active‐site, and local coordination effects, revealing two activation mechanisms: dopant‐driven (Rh@MO2) and coordination‐mediated (Fe@ZrO2).
Ziyuan Li   +5 more
wiley   +1 more source

HIGH-SPEED MULTIPLIER DESIGN BASED ON AN OPTIMIZED PARALLEL PREFIX TREE ARCHITECTURE

open access: yesInternational Journal of Advances in Signal and Image Sciences
Multiplication is a fundamental arithmetic operation, central to the performance of arithmetic and logic units (ALUs) in nearly all electronic systems. As such, the design and optimization of multipliers play a crucial role in improving the efficiency of
D. V. N. Bharathi, Y Varthamanan
doaj   +1 more source

Constructing Test Suites for Real-Time Embedded Systems Under Input Timing Constraints

open access: yesIEEE Access, 2019
Testing of real-time embedded systems (RTESs) under input timing constraints is a critical issue. Models which can specify timing constraints have respective merits and demerits and test suites which can cover more input possibilities and detect more ...
Yunlong Sheng, Shouda Jiang, Changan Wei
doaj   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

open access: yesAdvanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song   +14 more
wiley   +1 more source

Using boolean circuits for the parallel computation of queries

open access: yesJournal of Computer Science and Technology, 2001
We present partial results of a research project in which we use boolean circuits as a parallel computation model for the expression of queries to relational databases.
Edilma Olinda Gagliardi   +3 more
doaj  

Accelerated Discovery of Topological Conductors for Nanoscale Interconnects

open access: yesAdvanced Science, EarlyView.
Copper interconnects exhibit a sharp increase in resistivity at ultra‐scaled dimensions, threatening continued miniaturization of integrated circuits. The gapless surface states of topological semimetals provide conduction channels resistant to localization.
Alexander C. Tyner   +7 more
wiley   +1 more source

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