A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
On the computational complexity of determining the solvability or unsolvability of the equation 𝑋²-𝐷𝑌²=-1 [PDF]
, 1980 Jeffrey C. Lagarias
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Hexagonal-Grid-Layout Image Segmentation Using Shock Filters: Computational Complexity Case Study for Microarray Image Analysis Related to Machine Learning Approaches. [PDF]
Sensors (Basel), 2023 Baloi A +5 more
europepmc +1 more source
Corrections to “The Computation and Communication Complexity of a Parallel Banded System Solver” [PDF]
, 1985 Duncan H. Lawrie, Ahmed Sameh
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Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Computation and Complexity [PDF]
, 2019 Algorithmics, computation, optimization, complexity, combinatorics and knowledge representation are closely related sub-areas of Theoretical Computer Science. The following summary presents short descriptions of the twelve chapters in this topical part.
openaire +2 more sources
FEBS Open Bio, EarlyView.Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
A Novel, Low Computational Complexity, Parallel Swarm Algorithm for Application in Low-Energy Devices. [PDF]
Sensors (Basel), 2021 Długosz Z +3 more
europepmc +1 more source