Results 51 to 60 of about 828,043 (333)
The Complexity of Mental Integer Addition
Journal of Numerical Cognition, 2020 An important paradigm in modeling the complexity of mathematical tasks relies on computational complexity theory, in which complexity is measured through the resources (time, space) taken by a Turing machine to carry out the task.
Stefan Buijsman, Markus Pantsar
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Entropy, 2020 Sources that generate symbolic sequences with algorithmic nature may differ in statistical complexity because they create structures that follow algorithmic schemes, rather than generating symbols from a probabilistic function assuming independence.
Jorge M. Silva +3 more
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A Computable Economist’s Perspective on Computational Complexity [PDF]
, 2007 A computable economist's view of the world of computational complexity theory is described. This means the model of computation underpinning theories of computational complexity plays a central role.
Vela Velupillai, K.
core
Logical strength of complexity theory and a formalization of the PCP theorem in bounded arithmetic
, 2015 We present several known formalizations of theorems from computational complexity in bounded arithmetic and formalize the PCP theorem in the theory PV1 (no formalization of this theorem was known).
Pich, Ján
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Smoothed Complexity Theory [PDF]
, 2012 Smoothed analysis is a new way of analyzing algorithms introduced by Spielman and Teng (J. ACM, 2004). Classical methods like worst-case or average-case analysis have accompanying complexity classes, like P and AvgP, respectively.
A. Bogdanov +18 more
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Parameterized Uniform Complexity in Numerics: from Smooth to Analytic, from NP-hard to Polytime [PDF]
, 2012 The synthesis of classical Computational Complexity Theory with Recursive Analysis provides a quantitative foundation to reliable numerics. Here the operators of maximization, integration, and solving ordinary differential equations are known to map ...
Kawamura, Akitoshi +3 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source