Results 61 to 70 of about 4,782 (266)

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Frequency : Psychological and Methodological Considerations [PDF]

Construction Grammar is one of the fastest-growing branches of functional syntax. Bringing together an international team of scholars, this handbook provides a complete overview of the current issues and applications in this approach.
Hilpert, Martin
core   +2 more sources

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

Fluid construction grammar: The new kid on the block [PDF]

, 2012
Trabajo presentado a la 13th 13th Conference of the European Association for Computational Linguistics (EACL).Cognitive linguistics has reached a stage of maturity where many researchers are looking for an explicit formal grounding of their work ...
Beuls, Katrien, Wellens, Pieter, Steels, Luc, van Trijp, Remi, Beuls, Katrien; id_orcid, Trijp, Remi van   +5 more
core  

An integrated architecture for shallow and deep processing [PDF]

, 2011
We present an architecture for the integration of shallow and deep NLP components which is aimed at flexible combination of different language technologies for a range of practical current and future applications.
Müller, Stefan, Uszkoreit, Hans, Xu, Feiyu, Schäfer, Ulrich, Siegel, Melanie, Crysmann, Berthold, Frank, Anette, Kiefer, Bernd, Piskorski, Jakub, Neumann, Günter, Krieger, Hans-Ulrich, Becker, Markus   +11 more
core   +1 more source

Polarization Dynamics in Ferroelectrics: Insights Enabled by Machine Learning Molecular Dynamics

Advanced Science, EarlyView.
Machine learning molecular dynamics is presented as a route to capture polarization switching, domain wall kinetics, topological polar textures, and polar mechanical coupling beyond the limits of conventional atomistic methods. This Perspective surveys recent progress and identifies key methodological directions, including long‐range electrostatics ...
Dongyu Bai, Ri He, Junxian Liu, Liangzhi Kou   +3 more
wiley   +1 more source

MVG-DMA: A multi-view graph with dynamic multi-head attention-based transformer encoder for software requirements classification

Alexandria Engineering Journal
Software requirements classification is most important for software quality assurance. Existing graph-based methods fail to capture the syntactic, semantic, and contextual depth of requirement sentences.
Saratha P, Saswati Mukherjee, Rene Robin C R   +2 more
doaj   +1 more source

Case Studies in Fluid Construction Grammar The Verb Phase [PDF]

This book shows that construction grammar gives us also a powerful new way to conceive and implement operational parsing and production systems, which could be used as a basic component of a wide range of Artificial Intelligence applications, such as ...
Beuls, Katrien., Steels, Luc.
core