Results 101 to 110 of about 17,712,238 (346)

Weather-responsive adaptive shading through biobased and bioinspired hygromorphic 4D-printing

Nature Communications
In response to the global challenge of reducing carbon emissions and energy consumption from regulating indoor climates, we investigate the applicability of biobased cellulosic materials and bioinspired 4D-printing for weather-responsive adaptive shading
Tiffany Cheng, Yasaman Tahouni, Ekin Sila Sahin, Kim Ulrich, Silvia Lajewski, Christian Bonten, Dylan Wood, Jürgen Rühe, Thomas Speck, Achim Menges   +9 more
doaj   +1 more source

Computer-Aided Vaccine Design [PDF]

Human Vaccines & Immunotherapeutics, 2013
Vaccines, and their discovery, are topics of singular importance in present-day biomedical science. The discovery of vaccines has hitherto been primarily empirical in nature, and it is only now that this is giving way, albeit very slowly, to a more rational approach, supported and enhanced by computer-based methods.
openaire   +2 more sources

Design and analysis of fractional factorial experiments from the viewpoint of computational algebraic statistics

, 2010
We give an expository review of applications of computational algebraic statistics to design and analysis of fractional factorial experiments based on our recent works.
Adams W. W., Aoki S., Aoki S., Barba G., Box G. E. P., Cheng C. S., Cox D., Deng L. Y., Fontana R., Galetto F., Lang S., McCullagh P., Mukerjee R., Notari E. R., Pistone G., Pistone G., Pistone G., Sturmfels B., Wojtas W., Ye K. Q.   +19 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Computational Design of Synthetic Enzymes.

Chemical Reviews, 2018
We review the standard model for de novo computational design of enzymes, which primarily focuses on the development of an active-site geometry, composed of protein functional groups in orientations optimized to stabilize the transition state, for a ...
V. Vaissier Welborn, T. Head‐Gordon
semanticscholar   +1 more source

Supporting shape reinterpretation with eye tracking [PDF]

, 2011
It has been argued that reinterpretation is an essential process in design generation and idea exploration. However, computational design tools, such as computer-aided design systems, offer poor support for shape reinterpretation, and as such are not ...
Garner, Steven, Jowers, Iestyn, McKay, Alison, Pedreira, Nieves, Prats, Miquel   +4 more
core  

Computational Protein Design Using AND/OR Branch-and-Bound Search

, 2015
The computation of the global minimum energy conformation (GMEC) is an important and challenging topic in structure-based computational protein design.
Wu, Yuexin, Zeng, Jianyang, Zhou, Yichao
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Chemical ordering and magnetism in face-centered cubic CrCoNi alloy

npj Computational Materials
The impact of magnetism on chemical ordering in face-centered cubic CrCoNi medium entropy alloy is studied by a combination of ab initio simulations, machine learning potentials, and Monte Carlo simulations.
Sheuly Ghosh, Katharina Ueltzen, Janine George, Jörg Neugebauer, Fritz Körmann   +4 more
doaj   +1 more source