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The Walls of Computer Design

2006
Most of the work of the computer architect today has to do with bridging the well-known gigantic gap between processor speed and memory access time. However, other significant challenges are looming on the horizon. For one thing, higher device density and smaller design rules are increasing the sensitivity of circuits to outside radiation events. Also,
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The computability of architectural design

Proceedings of the 5th Jerusalem Conference on Information Technology, 1990. 'Next Decade in Information Technology', 2002
Two approaches, expressed in terms of mappings between design and computation, are explored with the intention of clarifying the relationship between the theories of design and computation. First, the relationship between models of the design process and computational search strategies is explored.
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Computational Enzyme Design

Angewandte Chemie International Edition, 2013
Abstract Recent developments in computational chemistry and biology have come together in the “inside‐out” approach to enzyme engineering. Proteins have been designed to catalyze reactions not previously accelerated in nature. Some of these proteins fold and act as catalysts, but the success rate is still low.
Gert, Kiss   +4 more
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Computational design of antibodies

Current Opinion in Structural Biology, 2018
Antibody design aims to create new antibodies with biological activity that can be used in therapy and research. Traditional methods for antibody discovery, such as animal immunization and large-scale library screening, generate antibodies that bind to the target of interest, but do not necessarily have the desired functional effect.
Sharon, Fischman, Yanay, Ofran
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Computer-aided design for quantum computation

Proceedings of the International Conference on Computer-Aided Design, 2018
Quantum computation is currently moving from an academic idea to a practical reality. The recent past has seen tremendous progress in the physical implementation of corresponding quantum computers - also involving big players such as IBM, Google, Intel, Rigetti, Microsoft, and Alibaba.
Robert Wille   +2 more
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The History of Design in Computing

IEEE Annals of the History of Computing, 2018
In this issue of the Annals, we are pleased to provide very different but equally unique contributions on the history of design in computing.
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Designing the human-computer interface

ACM SIGCSE Bulletin, 1982
There is a growing awareness in the academic and industrial computing communities of the need to introduce human factors considerations into the design of computer systems. At the School of Information and Computer Science of the Georgia Institute of Technology, this need is being met through a well-funded graduate research program in the human factors
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COMPUTING IN A DESIGN CURRICULUM

European Journal of Engineering Education, 1978
J. Davison, W. Hills
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The challenge of predicting distal active site mutations in computational enzyme design

Wiley Interdisciplinary Reviews: Computational Molecular Science, 2021
Silvia Osuna
exaly  

Automated computer design

Preprints of papers presented at the 14th national meeting of the Association for Computing Machinery on - ACM '59, 1959
John P. Malbrain, Anthony V. Banes
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