Results 11 to 20 of about 233,268 (268)

Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences

open access: yeseLife, 2018
Disentangling the effect on genomic diversity of natural selection from that of demography is notoriously difficult, but necessary to properly reconstruct the history of species.
Fanny Pouyet   +3 more
doaj   +1 more source

Computational modelling of plasticity-led evolution

open access: yesBiophysical Reviews, 2022
Plasticity-led evolution is a form of evolution where a change in the environment induces novel traits via phenotypic plasticity, after which the novel traits are genetically accommodated over generations under the novel environment. This mode of evolution is expected to resolve the problem of gradualism (i.e., evolution by the slow accumulation of ...
Eden Tian Hwa Ng, Akira R. Kinjo
openaire   +3 more sources

Population-level diversity-disease relationship (p-DDR) in the human microbiome associated diseases

open access: yesComputational and Structural Biotechnology Journal, 2021
Diversity-disease relationship (DDR) is a de facto standard analysis in the studies of human microbiome associated diseases (MADs). For example, the species richness or Shannon entropy are routinely compared between the healthy and diseased groups ...
Wendy Li, Zhanshan (Sam) Ma
doaj   +1 more source

Evolutions equations in computational anatomy [PDF]

open access: yesNeuroImage, 2009
One of the main purposes in computational anatomy is the measurement and statistical study of anatomical variations in organs, notably in the brain or the heart. Over the last decade, our group has progressively developed several approaches for this problem, all related to the Riemannian geometry of groups of diffeomorphisms and the shape spaces on ...
Laurent, Younes   +2 more
openaire   +2 more sources

Localization of adaptive variants in human genomes using averaged one-dependence estimation

open access: yesNature Communications, 2018
Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from ...
Lauren Alpert Sugden   +5 more
doaj   +1 more source

New genome assembly of the barn owl (Tyto alba alba)

open access: yesEcology and Evolution, 2020
New genomic tools open doors to study ecology, evolution, and population genomics of wild animals. For the Barn owl species complex, a cosmopolitan nocturnal raptor, a very fragmented draft genome was assembled for the American species (Tyto furcata ...
Anne‐Lyse Ducrest   +13 more
doaj   +1 more source

Niche-Neutral Continuum Seems to Explain the Global Niche Differentiation and Local Drift of the Human Digestive Tract Microbiome

open access: yesFrontiers in Microbiology, 2022
The human digestive tract (DT) is differentiated into diverse niches and harbors the greatest microbiome diversity of our bodies. Segata et al. (2012) found that the microbiome of diverse habitats along the DT may be classified as four categories or ...
Hongju (Daisy) Chen   +3 more
doaj   +1 more source

Quantifying the human vaginal community state types (CSTs) with the species specificity index [PDF]

open access: yesPeerJ, 2017
The five community state types (CSTs) first identified by Ravel et al. (2011) offered a powerful scheme to classify the states of human vaginal microbial communities (HVMC).
Zhanshan (Sam) Ma, Lianwei Li
doaj   +2 more sources

Evolution of Human Computer Interaction [PDF]

open access: yesScientific Visualization, 2020
The work is devoted to the review of the development the human-computer interaction. In the first sections the history of computing in the "pre-computer" era is briefly described and then the early history of modern computing, methods of the first computers controlling and the tasks of programmers at this stage are described.
openaire   +2 more sources

Functional and transcriptional connectivity of communities in breast cancer co-expression networks

open access: yesApplied Network Science, 2019
Transcriptional co-expression networks represent the concerted gene regulation programs by means of statistical inference of co-expression patterns. The rich phenomenology of transcriptional processes behind complex phenotypes such as cancer, is often ...
Guillermo de Anda-Jáuregui   +3 more
doaj   +1 more source

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