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Recombination's omnipresence in nature is one of the most intriguing problems in evolutionary biology. The question of why recombination exhibits certain general features is no less interesting than that of why it exists at all.
Sviatoslav Rybnikov +2 more
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Understanding individual decisions in a world where communications and information move instantly via cell phones and the internet, contributes to the development and implementation of policies aimed at stopping or ameliorating the spread of diseases. In
Asma Azizi +4 more
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Assessing and Interpreting the Within-Body Biogeography of Human Microbiome Diversity
A human body hosts a relatively independent microbiome including five major regional biomes (i.e., airway, oral, gut, skin, and urogenital). Each of them may possess different regional characteristics with important implications to our health and ...
Zhanshan Ma +5 more
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Semen Microbiome Biogeography: An Analysis Based on a Chinese Population Study
Investigating inter-subject heterogeneity (or spatial distribution) of human semen microbiome diversity is of important significance. Theoretically, the spatial distribution of biodiversity constitutes the core of microbiome biogeography.
Zhanshan Ma, Zhanshan Ma, Lianwei Li
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The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
AbstractComputers and computing emerged within a lifetime and completely changed our world. Although their history is brief, the change they precipitated has been rapid and constant. Today’s world would be unimaginably different without these machines. Not necessarily worse, but certainly slower, static, disconnected, and poorer.
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The behavioral and neuronal responses of the males of two closely related species of mice (Mus musculus wagneri, M. spicilegus) to the urine odors of estrus con- and heterospecific females were studied.
E. V. Kotenkova +2 more
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Measuring single cell divisions in human tissues from multi-region sequencing data
Quantifying somatic evolutionary processes in cancer and healthy tissue is a challenge. Here, the authors use single time point multi-region sampling of cancer and normal tissue, combined with evolutionary theory, to quantify in vivo mutation and cell ...
Benjamin Werner +14 more
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The human virome is a critical component of the human microbiome, and it is believed to hold the richest diversity within human microbiomes. Yet, the inter-individual scaling (changes) of the human virome has not been formally investigated to the best of
Wanmeng Xiao +3 more
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