Results 161 to 170 of about 312,909 (299)

Computational Fluid Dynamics Simulations to Personalize Nasal Irrigations

open access: yesJournal of Personalized Medicine
Background/Objectives: Proper nasal irrigation techniques are essential for treating nasal and sinus conditions, influencing drug delivery efficiency and patient comfort. This study evaluates how different head positions—upright, right-tilted, and left-tilted—affect the distribution of saline solution in the nasal cavity and maxillary sinus using ...
Thomas Radulesco   +6 more
openaire   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

open access: yesAdvanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery   +10 more
wiley   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

CFD Analysis on the Occurrence of Cavitations in the Water-cooling Pipes of Converter

open access: yesKongzhi Yu Xinxi Jishu, 2014
Based on the mechanism analysis of cavitations in terms of the fluid dynamics, a 3-dimensional model of 90° bend tube was established as an example of 90° bend of cooling system for converter. CFD(computational fluid dynamics) numerical simulation of the
ZHU Hui, WANG Hanqing
doaj  

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra   +7 more
wiley   +1 more source

Shapeshifting Liquid Metal Droplets for Soft Fluidic Machines

open access: yesAdvanced Materials, EarlyView.
This study presented a liquid metal shape shifting strategy which harnesses Lorentz force, surface tension and fluid instabilities to achieve autonomous fluidic power. By using a liquid metal droplet as a mobile current carrier, this strategy enables the development of low‐voltage, self‐oscillating pumps that outperform existing soft pumps.
Saba Firouznia   +5 more
wiley   +1 more source

Probing Cellular Activity Via Charge‐Sensitive Quantum Nanoprobes

open access: yesAdvanced Materials, EarlyView.
A new quantum sensing modality detects shifts in zero‐field splitting caused by charge rearrangement with diamond nanocrystals in response to cellular activity. These electric‐field‐driven effects provide an alternative to temperature‐based interpretations, enabling real‐time, single‐cell readout of inflammation.
Uri Zvi   +16 more
wiley   +1 more source

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