Results 31 to 40 of about 39,404 (265)

Numerical simulation of performance and emission of marine diesel engine under different gravity conditions

Advances in Mechanical Engineering, 2020
A computational fluid dynamics model of the marine diesel engine was established and validated, and the simulation studies were carried out using this model.
Xiuwei Lu, Peng Geng
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Aeroacoustic Simulation of an Owl Wing Cross-section Using Computational Fluid Dynamics

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2022
In this study, we aim to investigate the low noise flights of owls in terms of aerodynamics. The flow around cross-section of an owl wing, which is known for its nearly silent flight, is numerically analyzed using Computational Fluid Dynamics (CFD).
Ferit Yıldız, Sedat Tokgoz
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Computational Fluid Dynamics–Discrete Phase Method Simulations in Process Engineering: A Review of Recent Progress

Applied Sciences
Complex fluid–solid systems generally exist in process engineering. The cognition of complex flow systems depends on numerical and experimental methods. The computational fluid dynamics–discrete phase method simulation based on coarsening technology has ...
Xiaolian Yang, Te Xi, Yebo Qin, Hui Zhang, Yongwei Wang   +4 more
doaj   +1 more source

Computational Fluid Dynamics Simulation of Multiphase Flow in Structured Packings

Journal of Applied Mathematics, 2012
A volume of fluid multiphase flow model was used to investigate the effective area and the created liquid film in the structured packings. The computational results revealed that the gas and liquid flow rates play significant roles in the effective ...
Saeed Shojaee, Seyyed Hossein Hosseini, Behzad Saeedi Razavi   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Computational fluid dynamics simulation of Hyperloop pod predicting laminar–turbulent transition

Railway Engineering Science, 2020
Three-dimensional compressible flow simulations were conducted to develop a Hyperloop pod. The novelty is the usage of Gamma transition model, in which the transition from laminar to turbulent flow can be predicted.
Nathalie Nick, Yohei Sato
doaj   +1 more source