Results 51 to 60 of about 4,687,832 (367)

Analysis of moving least squares approximation revisited

open access: yes, 2015
In this article the error estimation of the moving least squares approximation is provided for functions in fractional order Sobolev spaces. The analysis presented in this paper extends the previous estimations and explains some unnoticed mathematical ...
Mirzaei, Davoud
core   +1 more source

Computational reverse mathematics and foundational analysis [PDF]

open access: yes, 2018
Reverse mathematics studies which subsystems of second order arithmetic are equivalent to key theorems of ordinary, non-set-theoretic mathematics. The main philosophical application of reverse mathematics proposed thus far is foundational analysis, which
Eastaugh, Benedict
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Computational Thinking and Mathematics

open access: yes, 2023
This chapter deals with the recent development of Computational Thinking (CT) in the curricula of many countries, principally in mathematics. It aims at discussing, broadly, how CT changes the mathematical activity and impacts mathematical contents. More precisely, we study the relations between mathematics, computer science, mathematical thinking and ...
Broley, Laura   +4 more
openaire   +2 more sources

Computational Literacy and “The Big Picture” Concerning Computers in Mathematics Education

open access: yes, 2018
This article develops some ideas concerning the “big picture” of how using computers might fundamentally change learning, with an emphasis on mathematics (and, more generally, STEM education).
A. diSessa
semanticscholar   +1 more source

Using Graphing Calculators to Integrate Mathematics and Science [PDF]

open access: yes, 1997
The computational, graphing, statistical and programming capabilities of today’s graphing calculators make it possible for teachers and students to explore aspects of functions and investigate real-world situations in ways that were previously ...
Garofalo, J., Pullano, F.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Improving The Quality Of The Mathematics Education: The Malaysian Experience [PDF]

open access: yes, 2011
Improving the quality of teaching and learning of mathematics has always been a major concern of mathematics educators. The four recurring and inter-related issues often raised in the development of a mathematics curriculum are: “What type of ...
Prof. Noor Azlan , Ahmad Zanzali
core  

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

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