Results 161 to 170 of about 25,655 (286)

Physics-Based Modeling of Sparse Single-Cell Hi-C Uncovers Structural and Epigenetic Variability. [PDF]

Int J Mol Sci
Vercellone F, Kundu S, Esposito A, Chiariello AM, Conte M, Abraham A, Fontana A, Di Pierno F, Guha S, Di Carluccio C, Olimpo M, Nicodemi M, Casale FP, Bianco S.   +13 more
europepmc   +1 more source

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

The sequence alignment problem: boundary conditions as the unifying principle. [PDF]

Brief Bioinform
Gagniuc PA, Gagniuc E.
europepmc   +1 more source

Partitioning sparse rectangular matrices for parallel computing of AAtX

, 1999
Cataloged from PDF version of article.Includes bibliographical references.Many scientific applications involve repeated sparse matrix-vector and matrixtranspose-vector product computations.
Uçar, Bora
core  

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

MCMC Methods for Multi-Response Generalized Linear Mixed Models: The MCMCglmm R Package

Generalized linear mixed models provide a flexible framework for modeling a range of data, although with non-Gaussian response variables the likelihood cannot be obtained in closed form.
Jarrod D. Hadfield
core  

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

Near-field localization of distributed targets based on exact spherical-wave model

Tongxin xuebao
To mitigate the model mismatch caused by Fresnel approximations in near-field distributed-target localization and the high computational burden of compressive-sensing-based methods, a near-field distributed-target localization approach was proposed based
Liu Yapeng, Gao Hongyuan, Wang Mingxing, Wu Linlong   +3 more
doaj  

Beyond Single Descriptors: Complementary Feature Learning for Image Matching. [PDF]

J Imaging
Yu X, Feng Y, Li X.
europepmc   +1 more source

stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics

Advanced Science, EarlyView.
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang, Yan Wang, Luonan Chen, Chunman Zuo   +3 more
wiley   +1 more source