Results 91 to 100 of about 1,237,196 (247)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Applications of computational modeling in ballistics [PDF]

The development of the technology of ballistics as applied to gun launched Army weapon systems is the main objective of research at the U.S. Army Ballistic Research Laboratory (BRL).
Sturek, Walter B.
core   +1 more source

Long time dynamics and coherent states in nonlinear wave equations

, 2016
We discuss recent progress in finding all coherent states supported by nonlinear wave equations, their stability and the long time behavior of nearby solutions.Comment: bases on the authors presentation at 2015 AMMCS-CAIMS Congress, to appear in Fields
A. Floer, A. Soffer, A. Soffer, A. Soffer, C.A. Pillet, D. Bambusi, E. Kirr, E. Kirr, E. Kirr, E. Kirr, E.W. Kirr, G. Zhou, H. Berestycki, H. Jeanjean, H. Jeanjean, H.A. Rose, I. M. Sigal, J.L. Marzuola, L. Nirenberg, M. Grillakis, M. Grillakis, M. Grillakis, M.I. Weinstein, M.I. Weinstein, P. H. Rabinowitz, P.-L. Lions, P.-L. Lions, P.G. Kevrekidis, R. A. Adams, R. K. Jackson, S. Cuccagna, S. Cuccagna, T. Cazenave, T. Mizumachi, T. Mizumachi, T.-P. Tsai, T.-P. Tsai, T.-P. Tsai, V. S. Buslaev, V. S. Buslaev, W.H. Aschbacher, Y. Guo, Y.-G. Oh   +42 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

BrainFrame: A node-level heterogeneous accelerator platform for neuron simulations

, 2017
Objective: The advent of High-Performance Computing (HPC) in recent years has led to its increasing use in brain study through computational models. The scale and complexity of such models are constantly increasing, leading to challenging computational ...
Al-Ars, Zaid, Chatzikonstantis, Georgios, De Zeeuw, Chris I., Kachris, Christoforos, Kukreja, Rahul, Rodopoulos, Dimitrios, Sidiropoulos, Harry, Smaragdos, Georgios, Soudris, Dimitrios, Sourdis, Ioannis, Strydis, Christos   +10 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Computational analysis of radiative micropolar fluid flow over a curved stretching sheet with viscous dissipation

Discover Applied Sciences
This study aims to investigate the mass and heat transmission in a magnetohydrodynamic micropolar fluid over a curved stretching sheet. It focuses on the combined effects of thermal radiation, chemical reaction and porosity via velocity, temperature ...
Bal Krishn Vaishnav, Sushila Choudhary, Prasun Choudhary, Kavita Jat, K. Loganathan, S. Eswaramoorthi   +5 more
doaj   +1 more source

Computational modeling to elucidate molecular mechanisms of epigenetic memory

, 2015
How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin statuses?
Alsing, Andrews, Ang, Angel, Arnold, Bannister, Barth, Beisel, Benecke, Bhattacharya, Binder, Black, Buscaino, Bushey, Canzio, Cowieson, David-Rus, Dayarian, Deal, Dodd, Fonseca, Freddolino, Gaffney, Grauffel, Greer, Grewal, Grigoryev, Hanna, Hathaway, Henikoff, Herranz, Hodges, Jacobs, Korolev, Korolev, Kouzarides, Ku, Kulaeva, Lin, Margreitter, Margueron, Mendenhall, Muller, Papp, Pasque, Peinado, Piana, Potoyan, Prohaska, Raghavan, Rohlf, Sanbonmatsu, Sanli, Schwab, Schwammle, Sedighi, So, Sontag, Steffen, Takahashi, Teif, Thon, Wocjan, Xu, Yang, Yuan, Zee, Zhang, Zhang   +68 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Numerical Study of an Oscillating Submerged Horizontal Plate Wave Energy Converter on the Southern Coast of Brazil: Parametric Analysis of the Variables Affecting Conversion Efficiency

Journal of Marine Science and Engineering
The utilization of ocean wave energy through environmentally sustainable technologies plays a pivotal role in the transition toward renewable energy sources.
Rodrigo Costa Batista, Elizaldo Domingues dos Santos, Luiz Alberto Oliveira Rocha, Mateus das Neves Gomes, Liércio André Isoldi   +4 more
doaj   +1 more source