Results 51 to 60 of about 771,325 (233)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Computational modelling of cracks in viscoplastic media [PDF]
A newly developed numerical model is used to simulate propagating cracks in a strain softening viscoplastic medium. The model allows the simulation of displacement discontinuities independently of a finite element mesh.
De Borst, R, Sluys, LJ, Wells, GN
core
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
A comparative study on mean value modelling of two-stroke marine diesel engine [PDF]
In the present paper, two mean value modelling approaches of varying complexity, capable of simulating two-stroke marine Diesel engines, are presented. Both approaches were implemented in the computational environment of MATLAB Simulink®. Simulation runs
Theotokatos, Gerasimos
core
How good are MatLab, Octave and Scilab for Computational Modelling? [PDF]
In this article we test the accuracy of three platforms used in computational modelling: MatLab, Octave and Scilab, running on i386 architecture and three operating systems (Windows, Ubuntu and Mac OS). We submitted them to numerical tests using standard
de Almeida, Eliana S. +2 more
core +2 more sources
Comparative Analysis of Audio Features for Unsupervised Speaker Change Detection
This study examines how ten different audio features, including MFCC, mel-spectrogram, chroma, and spectral contrast etc., influence speaker change detection (SCD) performance.
Alymzhan Toleu +4 more
doaj +1 more source
Kendall transformation brings a robust categorical representation of ordinal data
Kendall transformation is a conversion of an ordered feature into a vector of pairwise order relations between individual values. This way, it preserves ranking of observations and represents it in a categorical form.
Miron Bartosz Kursa
doaj +1 more source
Praznik: High performance information-based feature selection
Information filters are an important class of feature selection methods. They bring together strong theoretical background, execution speed and high selection quality. The paper provides a brief review of said methods and introduces praznik, an R package
Miron B. Kursa
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Numerical modelling and simulation in sheet metal forming [PDF]
The application of numerical modelling and simulation in manufacturing technologies is looking back over about a 20–30 years history. In recent years, the role of modelling and simulation in engineering and in manufacturing industry has been continuously
Altan +8 more
core +1 more source

