Results 61 to 70 of about 771,325 (233)

ON FINDING THE RESULTANT OF TWO ENTIRE FUNCTIONS

open access: yesПроблемы анализа, 2020
Using Newton’s recurrent formulae, we find the product of values of an entire function of one variable in zeroes of another entire function. This allows to answer whether they have common zeros.
A. M. Kytmanov, E. K. Myshkina
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Predicting glaucomatous visual field deterioration through short multivariate time series modelling [PDF]

open access: yes, 2002
In bio-medical domains there are many applications involving the modelling of multivariate time series (MTS) data. One area that has been largely overlooked so far is the particular type of time series where the data set consists of a large ...
Liu, X, Swift, S
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Depth diversity gradients of macrophytes: Shape, drivers, and recent shifts

open access: yesEcology and Evolution, 2021
Investigating diversity gradients helps to understand biodiversity drivers and threats. However, one diversity gradient is rarely assessed, namely how plant species distribute along the depth gradient of lakes.
Anne Lewerentz   +2 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Towards a Convenient Category of Topological Domains [PDF]

open access: yes, 2003
We propose a category of topological spaces that promises to be convenient for the purposes of domain theory as a mathematical theory for modelling computation. Our notion of convenience presupposes the usual properties of domain theory, e.g.
Simpson, Alex
core   +1 more source

metaRange: A framework to build mechanistic range models

open access: yesMethods in Ecology and Evolution
Mechanistic or process‐based models offer great insights into the range dynamics of species facing non‐equilibrium conditions, such as climate and land‐use changes or invasive species.
Stefan Fallert   +2 more
doaj   +1 more source

Retrieving atmospheric turbulence information from regular commercial aircraft using Mode-S and ADS-B [PDF]

open access: yesAtmospheric Measurement Techniques, 2016
Navigational information broadcast by commercial aircraft in the form of Mode-S EHS (Mode-S Enhanced Surveillance) and ADS-B (Automatic Dependent Surveillance–Broadcast) messages can be considered a new source of upper tropospheric and lower ...
J. M. Kopeć   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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