Gram filtering and sinogram interpolation for pixel-basis in parallel-beam X-ray CT reconstruction
, 2020 The key aspect of parallel-beam X-ray CT is forward and back projection, but its computational burden continues to be an obstacle for applications.
Entezari, Alireza, Shu, Ziyu
core +1 more source
Validating Dose Uncertainty Estimates Produced by AUTODIRECT: An Automated Program to Evaluate Deformable Image Registration Accuracy. [PDF]
, 2017 Deformable image registration is a powerful tool for mapping information, such as radiation therapy dose calculations, from one computed tomography image to another. However, deformable image registration is susceptible to mapping errors.
Chen, Josephine +5 more
core +3 more sources
A Monte Carlo study of organ and effective doses of cone beam computed tomography (CBCT) scans in radiotherapy [PDF]
, 2017 Cone-beam CT (CBCT) scans utilized for image guided radiation therapy (IGRT) procedures have become an essential part of radiotherapy. The aim of this study was to assess organ and effective doses resulting from new CBCT scan protocols (head, thorax, and
Abuhaimed, Abdullah +2 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Spherical deconvolution of multichannel diffusion MRI data with non-Gaussian noise models and spatial regularization [PDF]
, 2015 Spherical deconvolution (SD) methods are widely used to estimate the intra-voxel white-matter fiber orientations from diffusion MRI data. However, while some of these methods assume a zero-mean Gaussian distribution for the underlying noise, its real ...
Aja-Fernández, Santiago +13 more
core +7 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
3D microwave tomography with huber regularization applied to realistic numerical breast phantoms [PDF]
, 2016 Quantitative active microwave imaging for breast cancer screening and therapy monitoring applications requires adequate reconstruction algorithms, in particular with regard to the nonlinearity and ill-posedness of the inverse problem.
Bai, Funing +2 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Computational and Phantom-Based Feasibility Study of 3D dcNCI With Ultra-Low-Field MRI
Frontiers in Physics, 2021 The possibility to directly and non-invasively localize neuronal activities in the human brain, as for instance by performing neuronal current imaging (NCI) via magnetic resonance imaging (MRI), would be a breakthrough in neuroscience. In order to assess
Nora Höfner +4 more
doaj +1 more source
Development of a GPU-based Monte Carlo dose calculation code for coupled electron-photon transport
, 2010 Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy.
Amitava Majumdar +24 more
core +1 more source