Results 81 to 90 of about 2,962,605 (298)

Assessment of a method for manufacturing realistic breast lesions for experimental investigations

open access: yesFrontiers in Physics
IntroductionThe development and optimization of novel diagnostic imaging prototypes heavily rely on experimental work. In radiology, this experimental work involves the use of phantoms.
Kristina Bliznakova   +3 more
doaj   +1 more source

A Database for Estimating Organ Dose for Chest and Head CT Scans for Arbitrary Spectra and Angular Tube Current Modulation [PDF]

open access: yes, 2012
Purpose: The purpose of this study was to develop a database for estimating organ dose in a voxelized patient model for coronary angiography and brain perfusion CT acquisitions with any spectra and angular tube current modulation setting.
Badal, Andreu   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Advancing pediatric organ dose assessment in radioiodine therapy with ICRP pediatric mesh-type reference computational phantoms

open access: yesNuclear Engineering and Technology
The present study provides updated S values (rT ← thyroid) for 30 radiosensitive organs/tissues for pediatric patients undergoing radioiodine therapy with iodine-131, utilizing the pediatric mesh-type reference computational phantoms (MRCPs) very ...
Chansoo Choi   +3 more
doaj   +1 more source

Development of whole-body representation and dose calculation in a commercial treatment planning system

open access: yesZeitschrift für Medizinische Physik, 2022
For the epidemiological evaluation of long-term side effects of radiotherapy patients, it is important to know the doses to organs and tissues everywhere in the patient.
Pascal Hauri   +8 more
doaj   +1 more source

Deep learning in computational microscopy [PDF]

open access: yes, 2019
We propose to use deep convolutional neural networks (DCNNs) to perform 2D and 3D computational imaging. Specifically, we investigate three different applications. We first try to solve the 3D inverse scattering problem based on learning a huge number of
Nehmetallah, George   +2 more
core   +1 more source

Computer-generated fMRI phantoms with motion–distortion interaction [PDF]

open access: yesMagnetic Resonance Imaging, 2007
As an extension of previous work on computer-generated phantoms, more accurate, realistic phantoms are generated by integrating image distortion and signal loss caused by susceptibility variations. With the addition of real motions and activations determined from actual functional MRI studies, these phantoms can be used by the fMRI community to assess ...
Ning, Xu   +5 more
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Statistical approach for human electromagnetic exposure assessment in future wireless ATTO-cell networks [PDF]

open access: yes, 2019
In this article, we study human electromagnetic exposure to the radiation of an ultra dense network of nodes integrated in a floor denoted as ATTO-cell floor, or ATTO-floor. ATTO-cells are a prospective 5 G wireless networking technology, in which humans
Demeester, Piet   +6 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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